Entity Details

Primary name HXD8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP13378
EntryNameHXD8_HUMAN
FullNameHomeobox protein Hox-D8
TaxID9606
Evidenceevidence at protein level
Length290
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesHOXD8

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008595 anterior/posterior axis specification, embryo
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048705 skeletal system morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR001827 Homeobox protein, antennapedia type, conserved siteSiteConserved site
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain

Diseases

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Interactions

8 interactions