Entity Details

Primary name HXB3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP14651
EntryNameHXB3_HUMAN
FullNameHomeobox protein Hox-B3
TaxID9606
Evidenceevidence at transcript level
Length431
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesHOXB3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0002244 hematopoietic progenitor cell differentiation
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0009952 anterior/posterior pattern specification
GO:0021546 rhombomere development
GO:0021615 glossopharyngeal nerve morphogenesis
GO:0030878 thyroid gland development
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048704 embryonic skeletal system morphogenesis
GO:0050767 regulation of neurogenesis
GO:0051216 cartilage development
GO:0060216 definitive hemopoiesis
GO:0060324 face development

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR001827 Homeobox protein, antennapedia type, conserved siteSiteConserved site
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain
IPR025281 Domain of unknown function DUF4074DomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
HXB3_HUMANHMGB1_HUMANBioGRID8890171 details
HXB3_HUMANCBP_HUMANBioGRID, HPRD11585930 details
HXB3_HUMANEP300_HUMANHPRD11585930 details