Entity Details

Primary name IBP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP18065
EntryNameIBP2_HUMAN
FullNameInsulin-like growth factor-binding protein 2
TaxID9606
Evidenceevidence at protein level
Length325
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesIGFBP2

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007165 signal transduction
GO:0007565 female pregnancy
GO:0007568 aging
GO:0007584 response to nutrient
GO:0009612 response to mechanical stimulus
GO:0010226 response to lithium ion
GO:0016324 apical plasma membrane
GO:0031410 cytoplasmic vesicle
GO:0031994 insulin-like growth factor I binding
GO:0031995 insulin-like growth factor II binding
GO:0032355 response to estradiol
GO:0032526 response to retinoic acid
GO:0032870 cellular response to hormone stimulus
GO:0040008 regulation of growth
GO:0042104 positive regulation of activated T cell proliferation
GO:0042493 response to drug
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway
GO:0043627 response to estrogen
GO:0044267 cellular protein metabolic process
GO:0051384 response to glucocorticoid
GO:0070062 extracellular exosome
GO:0090090 negative regulation of canonical Wnt signaling pathway

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000716 Thyroglobulin type-1DomainDomain
IPR000867 Insulin-like growth factor-binding protein, IGFBPDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR012210 Insulin-like growth factor binding protein 2FamilyFamily
IPR017891 Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved siteSiteConserved site
IPR022321 Insulin-like growth factor-binding protein family 1-6, chordataFamilyFamily
IPR036857 Thyroglobulin type-1 superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01277 MecaserminDrugbankbiotech