Entity Details

Primary name VCAM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP19320
EntryNameVCAM1_HUMAN
FullNameVascular cell adhesion protein 1
TaxID9606
Evidenceevidence at protein level
Length739
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesVCAM1

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0002102 podosome
GO:0002526 acute inflammatory response
GO:0002544 chronic inflammatory response
GO:0005178 integrin binding
GO:0005615 extracellular space
GO:0005769 early endosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005902 microvillus
GO:0007155 cell adhesion
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 leukocyte cell-cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007568 aging
GO:0007584 response to nutrient
GO:0008131 primary amine oxidase activity
GO:0009308 amine metabolic process
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010043 response to zinc ion
GO:0010212 response to ionizing radiation
GO:0019221 cytokine-mediated signaling pathway
GO:0022614 membrane to membrane docking
GO:0030175 filopodium
GO:0030183 B cell differentiation
GO:0030198 extracellular matrix organization
GO:0032496 response to lipopolysaccharide
GO:0034113 heterotypic cell-cell adhesion
GO:0035094 response to nicotine
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0042102 positive regulation of T cell proliferation
GO:0042383 sarcolemma
GO:0045177 apical part of cell
GO:0045471 response to ethanol
GO:0050776 regulation of immune response
GO:0050839 cell adhesion molecule binding
GO:0050901 leukocyte tethering or rolling
GO:0060326 cell chemotaxis
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060384 innervation
GO:0060945 cardiac neuron differentiation
GO:0070062 extracellular exosome
GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
GO:0071356 cellular response to tumor necrosis factor
GO:0140039 cell-cell adhesion in response to extracellular stimulus
GO:1904646 cellular response to amyloid-beta

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003987 Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminalDomainDomain
IPR003989 Vascular cell adhesion molecule-1FamilyFamily
IPR007110 Immunoglobulin-like domainDomainDomain
IPR008424 Immunoglobulin C2-setDomainDomain
IPR013098 Immunoglobulin I-setDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013151 ImmunoglobulinDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00898 EthanolDrugbanksmall molecule
DB01136 CarvedilolDrugbanksmall molecule
DB05399 SuccinobucolDrugbanksmall molecule
DB11338 Clove oilDrugbankbiotech