Entity Details

Primary name MSRE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP21757
EntryNameMSRE_HUMAN
FullNameMacrophage scavenger receptor types I and II
TaxID9606
Evidenceevidence at protein level
Length451
SequenceStatuscomplete
DateCreated1991-05-01
DateModified2021-06-02

Ontological Relatives

GenesMSR1

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0005044 scavenger receptor activity
GO:0005581 collagen trimer
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006898 receptor-mediated endocytosis
GO:0006911 phagocytosis, engulfment
GO:0009897 external side of plasma membrane
GO:0010629 negative regulation of gene expression
GO:0010744 positive regulation of macrophage derived foam cell differentiation
GO:0010886 positive regulation of cholesterol storage
GO:0016021 integral component of membrane
GO:0030169 low-density lipoprotein particle binding
GO:0030301 cholesterol transport
GO:0030666 endocytic vesicle membrane
GO:0034362 low-density lipoprotein particle
GO:0034381 plasma lipoprotein particle clearance
GO:0038024 cargo receptor activity
GO:0097242 amyloid-beta clearance

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR001190 SRCR domainDomainDomain
IPR003543 Macrophage scavenger receptor, Class A-I/IIFamilyFamily
IPR008160 Collagen triple helix repeatRepeatRepeat
IPR017448 SRCR-like domainDomainDomain
IPR036772 SRCR-like domain superfamilyFamilyHomologous superfamily

Diseases

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