Entity Details

Primary name BMP5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22003
EntryNameBMP5_HUMAN
FullNameBone morphogenetic protein 5
TaxID9606
Evidenceevidence at protein level
Length454
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesBMP5

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001503 ossification
GO:0003272 endocardial cushion formation
GO:0003323 type B pancreatic cell development
GO:0003344 pericardium morphogenesis
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010894 negative regulation of steroid biosynthetic process
GO:0021502 neural fold elevation formation
GO:0030509 BMP signaling pathway
GO:0030902 hindbrain development
GO:0031982 vesicle
GO:0032348 negative regulation of aldosterone biosynthetic process
GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048738 cardiac muscle tissue development
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051216 cartilage development
GO:0060037 pharyngeal system development
GO:0060395 SMAD protein signal transduction
GO:0060411 cardiac septum morphogenesis
GO:0060710 chorio-allantoic fusion
GO:0061384 heart trabecula morphogenesis
GO:0070700 BMP receptor binding
GO:0071676 negative regulation of mononuclear cell migration
GO:1900006 positive regulation of dendrite development
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1905069 allantois development
GO:2000065 negative regulation of cortisol biosynthetic process

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001111 TGF-beta, propeptideDomainDomain
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR015615 Transforming growth factor-beta-relatedFamilyFamily
IPR017948 Transforming growth factor beta, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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