Entity Details

Primary name COT2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP24468
EntryNameCOT2_HUMAN
FullNameCOUP transcription factor 2
TaxID9606
Evidenceevidence at protein level
Length414
SequenceStatuscomplete
DateCreated1992-03-01
DateModified2021-06-02

Ontological Relatives

GenesNR2F2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001764 neuron migration
GO:0001893 maternal placenta development
GO:0001937 negative regulation of endothelial cell proliferation
GO:0001972 retinoic acid binding
GO:0003084 positive regulation of systemic arterial blood pressure
GO:0003700 DNA-binding transcription factor activity
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007519 skeletal muscle tissue development
GO:0008270 zinc ion binding
GO:0008585 female gonad development
GO:0009566 fertilization
GO:0009952 anterior/posterior pattern specification
GO:0009956 radial pattern formation
GO:0010596 negative regulation of endothelial cell migration
GO:0030154 cell differentiation
GO:0030900 forebrain development
GO:0032355 response to estradiol
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048514 blood vessel morphogenesis
GO:0048856 anatomical structure development
GO:0060173 limb development
GO:0060674 placenta blood vessel development
GO:0060707 trophoblast giant cell differentiation
GO:0060838 lymphatic endothelial cell fate commitment

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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