Entity Details

Primary name PTPRM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP28827
EntryNamePTPRM_HUMAN
FullNameReceptor-type tyrosine-protein phosphatase mu
TaxID9606
Evidenceevidence at protein level
Length1452
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesPTPRM

GO terms

Show/Hide Table
GOName
GO:0001937 negative regulation of endothelial cell proliferation
GO:0004725 protein tyrosine phosphatase activity
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0006470 protein dephosphorylation
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007165 signal transduction
GO:0010596 negative regulation of endothelial cell migration
GO:0010842 retina layer formation
GO:0016525 negative regulation of angiogenesis
GO:0030027 lamellipodium
GO:0031175 neuron projection development
GO:0031290 retinal ganglion cell axon guidance
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0045296 cadherin binding
GO:0048471 perinuclear region of cytoplasm

Subcellular Location

Show/Hide Table
Subcellular Location
Membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR000998 MAM domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013151 ImmunoglobulinDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR041201 PTPRJ, transmembrane domainDomainDomain

Diseases

Show/Hide Table