Entity Details
Primary name |
SC5A2_HUMAN |
Entity type |
UniProt |
Source |
Source Link |
Details
Accession | P31639 |
EntryName | SC5A2_HUMAN |
FullName | Sodium/glucose cotransporter 2 |
TaxID | 9606 |
Evidence | evidence at transcript level |
Length | 672 |
SequenceStatus | complete |
DateCreated | 1993-07-01 |
DateModified | 2021-06-02 |
Subcellular Location
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Subcellular Location |
Membrane |
Domains
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Domain | Name | Category | Type |
IPR001734 | Sodium/solute symporter | Family | Family |
IPR018212 | Sodium/solute symporter, conserved site | Site | Conserved site |
IPR038377 | Sodium/glucose symporter superfamily | Family | Homologous superfamily |
Diseases
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Disease ID | Source | Name | Description |
233100 | OMIM | Renal glucosuria (GLYS) | A disorder characterized by persistent isolated glucosuria, normal fasting serum glucose concentration, decreased renal tubular resorption of glucose from the urine, and absence of any other signs of tubular dysfunction. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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Drug | Name | Source | Type |
DB01914 | D-glucose | Swissprot | small molecule |
DB06292 | Dapagliflozin | Drugbank | small molecule |
DB08907 | Canagliflozin | Drugbank | small molecule |
DB09038 | Empagliflozin | Drugbank | small molecule |
DB11827 | Ertugliflozin | Drugbank | small molecule |
Interactions
1 interaction