Entity Details

Primary name ARBK2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35626
EntryNameARBK2_HUMAN
FullNameBeta-adrenergic receptor kinase 2
TaxID9606
Evidenceevidence at protein level
Length688
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesGRK3

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0004703 G protein-coupled receptor kinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0031623 receptor internalization
GO:0047696 beta-adrenergic receptor kinase activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000239 GPCR kinaseFamilyFamily
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR016137 RGS domainDomainDomain
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR036305 RGS domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00171 ATPDrugbanksmall molecule