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Entity Details
Primary name
GRK6_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P43250
EntryName
GRK6_HUMAN
FullName
G protein-coupled receptor kinase 6
TaxID
9606
Evidence
evidence at protein level
Length
576
SequenceStatus
complete
DateCreated
1995-11-01
DateModified
2021-06-02
Ontological Relatives
Genes
GRK6
GO terms
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GO
Name
GO:0004703
G protein-coupled receptor kinase activity
GO:0005524
ATP binding
GO:0005886
plasma membrane
GO:0007186
G protein-coupled receptor signaling pathway
GO:0008277
regulation of G protein-coupled receptor signaling pathway
GO:0016020
membrane
GO:0016055
Wnt signaling pathway
GO:0047696
beta-adrenergic receptor kinase activity
Subcellular Location
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Subcellular Location
Membrane
Domains
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Domain
Name
Category
Type
IPR000239
GPCR kinase
Family
Family
IPR000719
Protein kinase domain
Domain
Domain
IPR000961
AGC-kinase, C-terminal
Domain
Domain
IPR008271
Serine/threonine-protein kinase, active site
Site
Active site
IPR011009
Protein kinase-like domain superfamily
Family
Homologous superfamily
IPR016137
RGS domain
Domain
Domain
IPR017441
Protein kinase, ATP binding site
Site
Binding site
IPR036305
RGS domain superfamily
Family
Homologous superfamily
Diseases
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Drugs
Show/Hide Table
Interactions
26 interactions
Interactor
Partner
Sources
Publications
Link
GRK6_HUMAN
PRS23_HUMAN
BioGRID, HPRD, IntAct
16169070
details
GRK6_HUMAN
GRK6_HUMAN
HPRD, MINT
10334944
20729810
details
GRK6_HUMAN
ITA5_HUMAN
BioGRID, IntAct
21988832
details
GRK6_HUMAN
A4_HUMAN
IntAct
32814053
details
GRK6_HUMAN
FSHR_HUMAN
BioGRID, HPRD
10379886
details
GRK6_HUMAN
SYUA_HUMAN
BioGRID, HPRD
10852916
details
GRK6_HUMAN
SYUB_HUMAN
BioGRID
10852916
details
GRK6_HUMAN
SYUG_HUMAN
BioGRID
10852916
details
GRK6_HUMAN
ADRB2_HUMAN
BioGRID, HPRD
24561123
8672451
9819198
details
GRK6_HUMAN
CSEN_HUMAN
BioGRID
17102134
details
GRK6_HUMAN
TA2R_HUMAN
BioGRID, HPRD
11504827
details
GRK6_HUMAN
FBX7_HUMAN
BioGRID
27503909
details
GRK6_HUMAN
HS90B_HUMAN
BioGRID, IntAct
19996089
22939624
details
GRK6_HUMAN
MLF1_HUMAN
IntAct
25036637
details
GRK6_HUMAN
MLF2_HUMAN
IntAct
25036637
details
GRK6_HUMAN
RECO_HUMAN
BioGRID, HPRD
12507501
details
GRK6_HUMAN
HS90A_HUMAN
BioGRID
19996089
22939624
details
GRK6_HUMAN
DDB1_HUMAN
BioGRID
22952844
details
GRK6_HUMAN
OPSD_HUMAN
HPRD
8366096
details
GRK6_HUMAN
LT4R1_HUMAN
HPRD
12077128
details
GRK6_HUMAN
NHRF1_HUMAN
HPRD
10446210
details
GRK6_HUMAN
GIT1_HUMAN
HPRD
9826657
details
GRK6_HUMAN
EDNRB_HUMAN
HPRD
9211925
details
GRK6_HUMAN
BKRB2_HUMAN
HPRD
11517230
details
GRK6_HUMAN
ACM3_HUMAN
HPRD
11856737
details
GRK6_HUMAN
EDNRA_HUMAN
HPRD
9211925
details
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