Entity Details

Primary name UTRN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP46939
EntryNameUTRN_HUMAN
FullNameUtrophin
TaxID9606
Evidenceevidence at protein level
Length3433
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesUTRN

GO terms

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GOName
GO:0001954 positive regulation of cell-matrix adhesion
GO:0003779 actin binding
GO:0005178 integrin binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0006936 muscle contraction
GO:0007517 muscle organ development
GO:0007528 neuromuscular junction development
GO:0008270 zinc ion binding
GO:0014894 response to denervation involved in regulation of muscle adaptation
GO:0016010 dystrophin-associated glycoprotein complex
GO:0016020 membrane
GO:0017166 vinculin binding
GO:0019901 protein kinase binding
GO:0030175 filopodium
GO:0030426 growth cone
GO:0030864 cortical actin cytoskeleton
GO:0031527 filopodium membrane
GO:0031594 neuromuscular junction
GO:0032991 protein-containing complex
GO:0042383 sarcolemma
GO:0045211 postsynaptic membrane
GO:0051015 actin filament binding
GO:0070062 extracellular exosome
GO:2000649 regulation of sodium ion transmembrane transporter activity

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm

Domains

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DomainNameCategoryType
IPR000433 Zinc finger, ZZ-typeDomainDomain
IPR001202 WW domainDomainDomain
IPR001589 Actinin-type actin-binding domain, conserved siteSiteConserved site
IPR001715 Calponin homology domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR015153 EF-hand domain, type 1DomainDomain
IPR015154 EF-hand domain, type 2DomainDomain
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR035436 Dystrophin/utrophinFamilyFamily
IPR036020 WW domain superfamilyFamilyHomologous superfamily
IPR036872 CH domain superfamilyFamilyHomologous superfamily
IPR043145 Zinc finger, ZZ-type superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule

Interactions

31 interactions

InteractorPartnerSourcesPublicationsLink
UTRN_HUMANDTNA_HUMANBioGRID, HPRD, MINT10767429 24981860 9701558 details
UTRN_HUMANDAG1_HUMANBioGRID, HPRD, IntAct, MINT10767429 10769203 30914516 details
UTRN_HUMANSNTB2_HUMANBioGRID, HPRD, IntAct10995443 24981860 8576247 details
UTRN_HUMANPTN12_HUMANBioGRID, HPRD, MINT15231748 details
UTRN_HUMANDISC1_HUMANBioGRID, IntAct17043677 31413325 details
UTRN_HUMANMARK2_HUMANBioGRID, IntAct19615732 19945424 details
UTRN_HUMANC1T9A_HUMANBioGRID, IntAct23414517 details
UTRN_HUMANITBP1_HUMANBioGRID, IntAct23414517 details
UTRN_HUMANSNTA1_HUMANBioGRID, HPRD, IntAct18468998 8576247 details
UTRN_HUMANCALM1_HUMANBioGRID10767429 details
UTRN_HUMANCALM2_HUMANBioGRID10767429 details
UTRN_HUMANCALM3_HUMANBioGRID10767429 details
UTRN_HUMANPTEN_HUMANBioGRID26561776 details
UTRN_HUMANSASH1_HUMANBioGRID30480076 details
UTRN_HUMANDTNB_HUMANBioGRID, HPRD, MINT10545507 24981860 details
UTRN_HUMANSNTB1_HUMANBioGRID, HPRD, IntAct24981860 8576247 details
UTRN_HUMANDMD_HUMANBioGRID, HPRD, IntAct10767429 28514442 details
UTRN_HUMANPP2BA_HUMANDIP18838687 details
UTRN_HUMANOBI1_HUMANIntAct31413325 details
UTRN_HUMANUTRN_HUMANBioGRID, HPRD10647184 10995443 details
UTRN_HUMANPGM5_HUMANBioGRID, HPRD7589238 7890770 details
UTRN_HUMANTERF1_HUMANBioGRID20811636 details
UTRN_HUMANTERF2_HUMANBioGRID20811636 details
UTRN_HUMANATOH1_HUMANBioGRID27542412 details
UTRN_HUMANPKHA2_HUMANBioGRID19786618 details
UTRN_HUMANNDE1_HUMANBioGRID22028625 details
UTRN_HUMANATG5_HUMANBioGRID33024031 details
UTRN_HUMANACTN2_HUMANHPRD12006649 details
UTRN_HUMANDRP2_HUMANHPRD10767429 details
UTRN_HUMANACTS_HUMANHPRD12006649 details
UTRN_HUMANMARH5_HUMANHPRD16936636 details