Entity Details

Primary name INAR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48551
EntryNameINAR2_HUMAN
FullNameInterferon alpha/beta receptor 2
TaxID9606
Evidenceevidence at protein level
Length515
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesIFNAR2

GO terms

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GOName
GO:0004896 cytokine receptor activity
GO:0004905 type I interferon receptor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0009615 response to virus
GO:0016021 integral component of membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019901 protein kinase binding
GO:0019962 type I interferon binding
GO:0035455 response to interferon-alpha
GO:0035456 response to interferon-beta
GO:0051607 defense response to virus
GO:0060337 type I interferon signaling pathway
GO:0060338 regulation of type I interferon-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR003961 Fibronectin type IIIDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015373 Interferon/interleukin receptor domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00008 Peginterferon alfa-2aDrugbankbiotech
DB00011 Interferon alfa-n1Drugbankbiotech
DB00018 Interferon alfa-n3Drugbankbiotech
DB00022 Peginterferon alfa-2bDrugbankbiotech
DB00034 Interferon alfa-2a, RecombinantDrugbankbiotech
DB00060 Interferon beta-1aDrugbankbiotech
DB00068 Interferon beta-1bDrugbankbiotech
DB00069 Interferon alfacon-1Drugbankbiotech
DB00105 Interferon alfa-2bDrugbankbiotech
DB05472 Human interferon omega-1Drugbankbiotech
DB06152 NylidrinDrugbanksmall molecule