Entity Details

Primary name RGS6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49758
EntryNameRGS6_HUMAN
FullNameRegulator of G-protein signaling 6
TaxID9606
Evidenceevidence at protein level
Length472
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesRGS6

GO terms

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GOName
GO:0005096 GTPase activator activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0008277 regulation of G protein-coupled receptor signaling pathway
GO:0009968 negative regulation of signal transduction
GO:0019898 extrinsic component of membrane
GO:0035556 intracellular signal transduction
GO:0043547 positive regulation of GTPase activity

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000591 DEP domainDomainDomain
IPR015898 G-protein gamma-like domainDomainDomain
IPR016137 RGS domainDomainDomain
IPR024066 RGS, subdomain 1/3FamilyHomologous superfamily
IPR036284 G-protein gamma-like domain superfamilyFamilyHomologous superfamily
IPR036305 RGS domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037956 RGS6, RGS domainDomainDomain
IPR040759 Regulator of G-protein signalling, DHEX domainDomainDomain

Diseases

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