Entity Details

Primary name IDH3A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP50213
EntryNameIDH3A_HUMAN
FullNameIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length366
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesIDH3A

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004449 isocitrate dehydrogenase (NAD+) activity
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005975 carbohydrate metabolic process
GO:0006099 tricarboxylic acid cycle
GO:0006102 isocitrate metabolic process
GO:0051287 NAD binding

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR004434 Isocitrate dehydrogenase NAD-dependentFamilyFamily
IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved siteSiteConserved site
IPR024084 Isopropylmalate dehydrogenase-like domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB06757 ManganeseDrugbanksmall molecule
DB09092 XanthinolDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule