Entity Details

Primary name PRRX1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP54821
EntryNamePRRX1_HUMAN
FullNamePaired mesoderm homeobox protein 1
TaxID9606
Evidenceevidence at protein level
Length245
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesPRRX1

GO terms

Show/Hide Table
GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0030326 embryonic limb morphogenesis
GO:0042472 inner ear morphogenesis
GO:0042474 middle ear morphogenesis
GO:0045880 positive regulation of smoothened signaling pathway
GO:0048664 neuron fate determination
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048844 artery morphogenesis
GO:0051216 cartilage development
GO:0060021 roof of mouth development
GO:0070570 regulation of neuron projection regeneration
GO:0071837 HMG box domain binding
GO:0097150 neuronal stem cell population maintenance
GO:0100026 positive regulation of DNA repair by transcription from RNA polymerase II promoter

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR003654 OAR domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR043378 Paired mesoderm homeobox protein 1/2FamilyFamily

Diseases

Show/Hide Table