Entity Details

Primary name ITA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP56199
EntryNameITA1_HUMAN
FullNameIntegrin alpha-1
TaxID9606
Evidenceevidence at protein level
Length1179
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesITGA1

GO terms

Show/Hide Table
GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001669 acrosomal vesicle
GO:0005102 signaling receptor binding
GO:0005518 collagen binding
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006936 muscle contraction
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0008285 negative regulation of cell population proliferation
GO:0008305 integrin complex
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0019903 protein phosphatase binding
GO:0030198 extracellular matrix organization
GO:0030593 neutrophil chemotaxis
GO:0032516 positive regulation of phosphoprotein phosphatase activity
GO:0034665 integrin alpha1-beta1 complex
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042311 vasodilation
GO:0043005 neuron projection
GO:0043204 perikaryon
GO:0043525 positive regulation of neuron apoptotic process
GO:0045121 membrane raft
GO:0045123 cellular extravasation
GO:0045178 basal part of cell
GO:0046872 metal ion binding
GO:0048812 neuron projection morphogenesis
GO:0070062 extracellular exosome
GO:0098639 collagen binding involved in cell-matrix adhesion

Subcellular Location

Show/Hide Table
Subcellular Location
Membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR000413 Integrin alpha chainFamilyFamily
IPR002035 von Willebrand factor, type ADomainDomain
IPR013517 FG-GAP repeatRepeatRepeat
IPR013519 Integrin alpha beta-propellorRepeatRepeat
IPR013649 Integrin alpha-2DomainDomain
IPR018184 Integrin alpha chain, C-terminal cytoplasmic region, conserved siteSiteConserved site
IPR028994 Integrin alpha, N-terminalFamilyHomologous superfamily
IPR032695 Integrin domain superfamilyFamilyHomologous superfamily
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table