Entity Details

Primary name NRX1B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP58400
EntryNameNRX1B_HUMAN
FullNameNeurexin-1-beta
TaxID9606
Evidenceevidence at protein level
Length472
SequenceStatuscomplete
DateCreated2001-11-16
DateModified2021-06-02

Ontological Relatives

GenesNRXN1

GO terms

Show/Hide Table
GOName
GO:0001525 angiogenesis
GO:0004888 transmembrane signaling receptor activity
GO:0005102 signaling receptor binding
GO:0005105 type 1 fibroblast growth factor receptor binding
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007158 neuron cell-cell adhesion
GO:0007165 signal transduction
GO:0007416 synapse assembly
GO:0007612 learning
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010739 positive regulation of protein kinase A signaling
GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0021707 cerebellar granule cell differentiation
GO:0023041 neuronal signal transduction
GO:0030139 endocytic vesicle
GO:0030534 adult behavior
GO:0031175 neuron projection development
GO:0031965 nuclear membrane
GO:0031982 vesicle
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0035176 social behavior
GO:0035418 protein localization to synapse
GO:0042734 presynaptic membrane
GO:0043025 neuronal cell body
GO:0044295 axonal growth cone
GO:0045184 establishment of protein localization
GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway
GO:0046872 metal ion binding
GO:0048306 calcium-dependent protein binding
GO:0050839 cell adhesion molecule binding
GO:0051490 negative regulation of filopodium assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0051965 positive regulation of synapse assembly
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071277 cellular response to calcium ion
GO:0071625 vocalization behavior
GO:0090126 protein-containing complex assembly involved in synapse maturation
GO:0097091 synaptic vesicle clustering
GO:0097104 postsynaptic membrane assembly
GO:0097105 presynaptic membrane assembly
GO:0097109 neuroligin family protein binding
GO:0097112 gamma-aminobutyric acid receptor clustering
GO:0097114 NMDA glutamate receptor clustering
GO:0097116 gephyrin clustering involved in postsynaptic density assembly
GO:0097117 guanylate kinase-associated protein clustering
GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly
GO:0097119 postsynaptic density protein 95 clustering
GO:0097120 receptor localization to synapse
GO:0098793 presynapse
GO:0099056 integral component of presynaptic membrane
GO:1900020 positive regulation of protein kinase C activity
GO:1903078 positive regulation of protein localization to plasma membrane
GO:1905520 positive regulation of presynaptic active zone assembly
GO:2000310 regulation of NMDA receptor activity
GO:2000311 regulation of AMPA receptor activity
GO:2000463 positive regulation of excitatory postsynaptic potential

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction

Domains

Show/Hide Table
DomainNameCategoryType
IPR001791 Laminin G domainDomainDomain
IPR003585 Neurexin/syndecan/glycophorin CDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR027789 Syndecan/Neurexin domainDomainDomain

Diseases

Show/Hide Table