Entity Details

Primary name RL11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP62913
EntryNameRL11_HUMAN
FullName60S ribosomal protein L11
TaxID9606
Evidenceevidence at protein level
Length178
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesRPL11

GO terms

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GOName
GO:0000027 ribosomal large subunit assembly
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0002181 cytoplasmic translation
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006364 rRNA processing
GO:0006412 translation
GO:0006413 translational initiation
GO:0006605 protein targeting
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0008097 5S rRNA binding
GO:0010628 positive regulation of gene expression
GO:0016020 membrane
GO:0019083 viral transcription
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0031625 ubiquitin protein ligase binding
GO:0032092 positive regulation of protein binding
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032991 protein-containing complex
GO:0034504 protein localization to nucleus
GO:0042273 ribosomal large subunit biogenesis
GO:0042788 polysomal ribosome
GO:0050821 protein stabilization
GO:0070062 extracellular exosome
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
GO:1904667 negative regulation of ubiquitin protein ligase activity
GO:1990948 ubiquitin ligase inhibitor activity
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process
GO:2000435 negative regulation of protein neddylation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR002132 Ribosomal protein L5FamilyFamily
IPR020929 Ribosomal protein L5, conserved siteSiteConserved site
IPR022803 Ribosomal protein L5 domain superfamilyFamilyHomologous superfamily
IPR031309 Ribosomal protein L5, C-terminalDomainDomain
IPR031310 Ribosomal protein L5, N-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB02494 (S)-3-phenyllactic acidDrugbanksmall molecule
DB07374 AnisomycinDrugbanksmall molecule
DB08437 PuromycinDrugbanksmall molecule

Interactions

54 interactions

InteractorPartnerSourcesPublicationsLink
RL11_HUMANMDM2_HUMANBioGRID, HPRD, I2D, IntAct, MINT12842086 14612427 15308643 15314173 15314174 16803902 17110929 17116689 17242401 17310983 17373842 18426907 18560357 19713960 20547751 20554519 21097889 21399665 21804542 21903592 21988832 22467867 23169665 23507139 23728348 23776465 26908445 27829214 27856536 29057323 29547122 29702115 30320499 30862720 31903119 32198344 32334023 32483207 32516735 details
RL11_HUMANKAT5_HUMANIntAct32814053 details
RL11_HUMANHEY1_HUMANBioGRID27129302 details
RL11_HUMANARFG1_HUMANBioGRID, IntAct21988832 details
RL11_HUMANBLMH_HUMANBioGRID, HPRD10353821 details
RL11_HUMANIGF1R_HUMANBioGRID, IntAct21988832 27684187 details
RL11_HUMANHPT_HUMANBioGRID, IntAct21988832 details
RL11_HUMANOSBL3_HUMANBioGRID, IntAct32296183 details
RL11_HUMANKR107_HUMANBioGRID, IntAct25416956 details
RL11_HUMANCDN2A_HUMANBioGRID14612427 22467867 details
RL11_HUMANGRWD1_HUMANBioGRID27856536 29991511 31903119 details
RL11_HUMANSTAT3_HUMANBioGRID, IntAct21988832 details
RL11_HUMANK1C40_HUMANBioGRID, IntAct25416956 details
RL11_HUMANPCNA_HUMANUniProt26030842 details
RL11_HUMANA4_HUMANBioGRID21244100 details
RL11_HUMANP73_HUMANBioGRID25301064 details
RL11_HUMANKCC2B_HUMANBioGRID, IntAct25416956 details
RL11_HUMANDNLI4_HUMANBioGRID22990118 details
RL11_HUMANSETB1_HUMANIntAct32814053 details
RL11_HUMANARF_HUMANBioGRID14612427 22467867 details
RL11_HUMANSENP1_HUMANBioGRID30024791 details
RL11_HUMANOGT1_HUMANBioGRID32994395 details
RL11_HUMANTIGAR_HUMANBioGRID, IntAct21988832 details
RL11_HUMANPML_HUMANBioGRID, HPRD15195100 23169665 details
RL11_HUMANPAIP2_HUMANBioGRID, IntAct21988832 details
RL11_HUMANIP6K1_HUMANBioGRID, IntAct32296183 details
RL11_HUMAN1433G_HUMANIntAct32814053 details
RL11_HUMANLMO3_HUMANIntAct32814053 details
RL11_HUMANDVL3_HUMANBioGRID, IntAct32296183 details
RL11_HUMANUBC9_HUMANBioGRID30024791 details
RL11_HUMANSENP8_HUMANMINT18274552 details
RL11_HUMANHSPB2_HUMANbhf-ucl, BioGRID26465331 details
RL11_HUMANRL23_HUMANBioGRID15308643 17116689 22939629 26344197 details
RL11_HUMANATM_HUMANBioGRID30252118 details
RL11_HUMANNOP56_HUMANBioGRID, IntAct12777385 22939629 26496610 details
RL11_HUMANRL5_HUMANBioGRID15308643 17116689 17242401 18560357 22939629 23169665 26344197 29547122 details
RL11_HUMANVHL_HUMANBioGRID23612971 details
RL11_HUMANP53_HUMANBioGRID14612427 15308643 22467867 23169665 23443559 31152661 32334023 details
RL11_HUMANMYC_HUMANBioGRID, MINT17599065 29467282 details
RL11_HUMANPELP1_HUMANBioGRID22190735 details
RL11_HUMANM3K14_HUMANIntAct14743216 details
RL11_HUMANRL4_HUMANBioGRID22939629 26344197 26908445 details
RL11_HUMANNFKB2_HUMANIntAct14743216 details
RL11_HUMANCSN9_HUMANBioGRID23776465 details
RL11_HUMANNOP53_HUMANBioGRID27829214 details
RL11_HUMANITA4_HUMANBioGRID22623428 details
RL11_HUMANRL22_HUMANBioGRID22939629 26344197 29207594 details
RL11_HUMANSOX2_HUMANBioGRID21280222 details
RL11_HUMANTBK1_HUMANIntAct14743216 details
RL11_HUMANZBTB1_HUMANBioGRID24657165 details
RL11_HUMANNEDD8_HUMANBioGRID, IntAct, MINT18274552 19713960 21145461 details
RL11_HUMANIKBB_HUMANIntAct14743216 details
RL11_HUMANHS90B_HUMANIntAct25910212 details
RL11_HUMANNEMO_HUMANIntAct14743216 details