Entity Details

Primary name IF4G2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP78344
EntryNameIF4G2_HUMAN
FullNameEukaryotic translation initiation factor 4 gamma 2
TaxID9606
Evidenceevidence at protein level
Length907
SequenceStatuscomplete
DateCreated2003-04-30
DateModified2021-06-02

Ontological Relatives

GenesEIF4G2

GO terms

Show/Hide Table
GOName
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003743 translation initiation factor activity
GO:0005829 cytosol
GO:0005912 adherens junction
GO:0006446 regulation of translational initiation
GO:0007507 heart development
GO:0008135 translation factor activity, RNA binding
GO:0008219 cell death
GO:0010507 negative regulation of autophagy
GO:0016020 membrane
GO:0016281 eukaryotic translation initiation factor 4F complex
GO:0030307 positive regulation of cell growth
GO:0030424 axon
GO:0034645 cellular macromolecule biosynthetic process
GO:0045296 cadherin binding
GO:0045727 positive regulation of translation
GO:0045773 positive regulation of axon extension
GO:0060999 positive regulation of dendritic spine development

Subcellular Location

Show/Hide Table

Domains

Show/Hide Table
DomainNameCategoryType
IPR003307 W2 domainDomainDomain
IPR003890 MIF4G-like, type 3DomainDomain
IPR003891 Initiation factor eIF-4 gamma, MA3DomainDomain
IPR016021 MIF4G-like domain superfamilyFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

29 interactions

InteractorPartnerSourcesPublicationsLink
IF4G2_HUMANSKIL_HUMANBioGRID, HPRD, MINT15231748 details
IF4G2_HUMANIF4A1_HUMANBioGRID, DIP, HPRD, IntAct, MINT10611228 16166382 16932749 22939629 23478064 28514442 29395067 9372926 details
IF4G2_HUMANRFA2_HUMANBioGRID, IntAct21988832 details
IF4G2_HUMANC1T9A_HUMANBioGRID, IntAct23414517 details
IF4G2_HUMANHSPB1_HUMANBioGRID, IntAct25277244 details
IF4G2_HUMANSUMO2_HUMANBioGRID32786267 details
IF4G2_HUMANCBP_HUMANBioGRID32238831 details
IF4G2_HUMANOGT1_HUMANBioGRID32994395 details
IF4G2_HUMANIF4A2_HUMANBioGRID, HPRD, IntAct11172724 17353931 29395067 details
IF4G2_HUMANIF2B_HUMANHPRD, MINT16932749 details
IF4G2_HUMANIF2A_HUMANMINT16932749 details
IF4G2_HUMANEIF3J_HUMANMINT16932749 details
IF4G2_HUMANTP4A3_HUMANIntAct17353931 details
IF4G2_HUMANCIAO1_HUMANIntAct17353931 details
IF4G2_HUMANGSTK1_HUMANIntAct17353931 details
IF4G2_HUMANOPTN_HUMANIntAct20195357 details
IF4G2_HUMANMKNK1_HUMANBioGRID, HPRD9878069 details
IF4G2_HUMANEIF3A_HUMANBioGRID, HPRD10611228 details
IF4G2_HUMANITA4_HUMANBioGRID22623428 details
IF4G2_HUMANRN126_HUMANBioGRID26508657 details
IF4G2_HUMANZBT7A_HUMANBioGRID28849590 details
IF4G2_HUMANYTHD2_HUMANBioGRID29395067 details
IF4G2_HUMANYTHD3_HUMANBioGRID29395067 details
IF4G2_HUMANZCCHV_HUMANBioGRID29395067 details
IF4G2_HUMANEST1A_HUMANBioGRID29395067 details
IF4G2_HUMANCASP3_HUMANHPRD11175261 details
IF4G2_HUMANIF5_HUMANHPRD11331597 details
IF4G2_HUMANNCBP1_HUMANHPRD15361857 details
IF4G2_HUMANIF4E_HUMANHPRD10394359 details