Entity Details

Primary name RED1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP78563
EntryNameRED1_HUMAN
FullNameDouble-stranded RNA-specific editase 1
TaxID9606
Evidenceevidence at protein level
Length741
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesADARB1

GO terms

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GOName
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006382 adenosine to inosine editing
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0007274 neuromuscular synaptic transmission
GO:0008251 tRNA-specific adenosine deaminase activity
GO:0008285 negative regulation of cell population proliferation
GO:0016553 base conversion or substitution editing
GO:0021610 facial nerve morphogenesis
GO:0021618 hypoglossal nerve morphogenesis
GO:0021965 spinal cord ventral commissure morphogenesis
GO:0030336 negative regulation of cell migration
GO:0035264 multicellular organism growth
GO:0042802 identical protein binding
GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045070 positive regulation of viral genome replication
GO:0045087 innate immune response
GO:0045202 synapse
GO:0046872 metal ion binding
GO:0050884 neuromuscular process controlling posture
GO:0051607 defense response to virus
GO:0051726 regulation of cell cycle
GO:0060384 innervation
GO:0060415 muscle tissue morphogenesis
GO:0061744 motor behavior
GO:0097049 motor neuron apoptotic process

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002466 Adenosine deaminase/editaseDomainDomain
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily
IPR014720 Double-stranded RNA-binding domainDomainDomain
IPR044458 ADAR2, first double-stranded RNA binding domainDomainDomain
IPR044459 ADAR2, second double-stranded RNA binding domainDomainDomain

Diseases

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