Entity Details

Primary name NR1H3
Entity type gene
Source Source Link

Details

PrimaryID10062
RefseqGeneNG_030392
SymbolNR1H3
Namenuclear receptor subfamily 1 group H member 3
Chromosome11
Location11p11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNR1H3_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0008270 zinc ion binding
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010867 positive regulation of triglyceride biosynthetic process
GO:0010875 positive regulation of cholesterol efflux
GO:0010887 negative regulation of cholesterol storage
GO:0015485 cholesterol binding
GO:0030154 cell differentiation
GO:0030522 intracellular receptor signaling pathway
GO:0032270 positive regulation of cellular protein metabolic process
GO:0032369 negative regulation of lipid transport
GO:0032376 positive regulation of cholesterol transport
GO:0032570 response to progesterone
GO:0032810 sterol response element binding
GO:0034145 positive regulation of toll-like receptor 4 signaling pathway
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0042632 cholesterol homeostasis
GO:0042752 regulation of circadian rhythm
GO:0043031 negative regulation of macrophage activation
GO:0043235 receptor complex
GO:0043277 apoptotic cell clearance
GO:0045723 positive regulation of fatty acid biosynthetic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048550 negative regulation of pinocytosis
GO:0050728 negative regulation of inflammatory response
GO:0051006 positive regulation of lipoprotein lipase activity
GO:0055088 lipid homeostasis
GO:0055092 sterol homeostasis
GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway
GO:0070328 triglyceride homeostasis
GO:0071222 cellular response to lipopolysaccharide
GO:0090188 negative regulation of pancreatic juice secretion
GO:0090341 negative regulation of secretion of lysosomal enzymes
GO:0090575 RNA polymerase II transcription regulator complex
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1903573 negative regulation of response to endoplasmic reticulum stress

Diseases

Show/Hide Table

Interactions

67 interactions

InteractorPartnerSourcesPublicationsLink
NR1H3EDF1BioGRID, HPRD, IntAct12040021 details
NR1H3NCOA1BioGRID, MINT15604093 20682316 25962847 details
NR1H3RXRABioGRID, DIP, HPRD, MINT12117567 15604093 15722453 20682316 8621574 9013544 details
NR1H3RXRGBioGRID, HPRD, IntAct, MINT15604093 21516116 25416956 25910212 31515488 32296183 details
NR1H3MSTO1BioGRID, IntAct21988832 details
NR1H3KDM1ABioGRID, MINT23455924 details
NR1H3SUV39H1BioGRID, MINT23455924 details
NR1H3RXRBBioGRID, HPRD, IntAct15604093 25416956 26871637 32296183 details
NR1H3MDFIBioGRID, IntAct25416956 25910212 32296183 details
NR1H3NCOR2IntAct26120082 details
NR1H3NCOR1BioGRID, HPRD, IntAct12663743 15604093 26120082 details
NR1H3MED1IntAct26120082 details
NR1H3GPANK1BioGRID, IntAct32296183 details
NR1H3BAG3BioGRID, IntAct32296183 details
NR1H3PPARABioGRID, DIP15722453 24713062 8621574 details
NR1H3PPARDBioGRID, DIP15722453 details
NR1H3PPARGBioGRID, DIP15722453 details
NR1H3LMNAIntAct32814053 details
NR1H3SPRED1IntAct32814053 details
NR1H3HTTIntAct32814053 details
NR1H3LZTR1BioGRID, IntAct20211142 details
NR1H3SS18L1BioGRID, IntAct20211142 details
NR1H3NR0B2BioGRID, HPRD12198243 27485016 details
NR1H3ZXDCBioGRID15604093 details
NR1H3KAT2BBioGRID15604093 details
NR1H3NCOA3BioGRID, HPRD15604093 details
NR1H3NCOA6BioGRID, HPRD12724417 15604093 details
NR1H3ACTN1BioGRID, HPRD15604093 details
NR1H3FOXO3BioGRID, HPRD15604093 details
NR1H3NRIP1BioGRID, HPRD10022764 15604093 details
NR1H3TMEM161ABioGRID, HPRD15604093 details
NR1H3ING3BioGRID, HPRD15604093 details
NR1H3NR3C1BioGRID22457708 details
NR1H3APPBioGRID21832049 details
NR1H3CEP350BioGRID15615782 details
NR1H3PSMC5BioGRID15604093 details
NR1H3UBE2IBioGRID27485016 details
NR1H3SYT1HPRD16143103 details
NR1H3HSP90AB1IntAct22939624 details
NR1H3MLF1IntAct25036637 details
NR1H3FKBP5IntAct25036637 details
NR1H3PTGES3LIntAct25036637 details
NR1H3PTGES3L-AARSD1IntAct25036637 details
NR1H3AARSD1IntAct25036637 details
NR1H3FKBPLIntAct25036637 details
NR1H3MEN1MINT25962847 details
NR1H3BARD1BioGRID19164445 24009820 details
NR1H3SIRT1BioGRID, HPRD17936707 details
NR1H3PIAS1BioGRID22969086 details
NR1H3HSP90AA1BioGRID22939624 details
NR1H3CCND1BioGRID27485016 details
NR1H3BBS5BioGRID27485016 details
NR1H3STAT1BioGRID27485016 details
NR1H3HDAC4BioGRID27485016 details
NR1H3RARAHPRD10022764 details
NR1H3EP300MINT25962847 details
NR1H3STRN4BioGRID, IntAct26186194 28514442 details
NR1H3DDI2BioGRID, IntAct26186194 28514442 details
NR1H3STRN3BioGRID, IntAct26186194 28514442 details
NR1H3PDE8ABioGRID, IntAct28514442 details
NR1H3STRNBioGRID, IntAct26186194 28514442 details
NR1H3MKLN1BioGRID26186194 details
NR1H3LAMTOR5BioGRID30692632 details
NR1H3SREBF1IntAct26120082 details
NR1H3FASNIntAct26120082 details
NR1H3HK1IntAct26120082 details
NR1H3PFKFB1IntAct26120082 details