Entity Details

Primary name NTCP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12908
EntryNameNTCP2_HUMAN
FullNameIleal sodium/bile acid cotransporter
TaxID9606
Evidenceevidence at protein level
Length348
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesSLC10A2

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0008508 bile acid:sodium symporter activity
GO:0015721 bile acid and bile salt transport
GO:0016324 apical plasma membrane

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3FamilyFamily
IPR004710 Bile acid:sodium symporterFamilyFamily
IPR030207 Solute carrier family 10 member 2FamilyFamily
IPR038770 Sodium/solute symporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00091 CyclosporineDrugbanksmall molecule
DB00577 ValaciclovirDrugbanksmall molecule
DB00787 AcyclovirDrugbanksmall molecule
DB01586 Ursodeoxycholic acidDrugbanksmall molecule
DB02123 Glycochenodeoxycholic AcidDrugbanksmall molecule
DB02659 Cholic AcidDrugbanksmall molecule
DB03619 Deoxycholic acidDrugbanksmall molecule
DB04348 Taurocholic acidDrugbanksmall molecule
DB09237 LevamlodipineDrugbanksmall molecule
DB13914 VolixibatDrugbanksmall molecule