Entity Details

Primary name ADORA2A
Entity type gene
Source Source Link

Details

PrimaryID135
RefseqGeneNG_052804
SymbolADORA2A
Nameadenosine A2a receptor
Chromosome22
Location22q11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsAA2AR_HUMAN

GO terms

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GOName
GO:0001609 G protein-coupled adenosine receptor activity
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0005882 intermediate filament
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006469 negative regulation of protein kinase activity
GO:0006909 phagocytosis
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0006968 cellular defense response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0007271 synaptic transmission, cholinergic
GO:0007417 central nervous system development
GO:0007596 blood coagulation
GO:0007600 sensory perception
GO:0007626 locomotory behavior
GO:0008015 blood circulation
GO:0008285 negative regulation of cell population proliferation
GO:0012505 endomembrane system
GO:0014049 positive regulation of glutamate secretion
GO:0014057 positive regulation of acetylcholine secretion, neurotransmission
GO:0014061 regulation of norepinephrine secretion
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0019899 enzyme binding
GO:0030425 dendrite
GO:0030673 axolemma
GO:0031000 response to caffeine
GO:0031802 type 5 metabotropic glutamate receptor binding
GO:0035249 synaptic transmission, glutamatergic
GO:0035810 positive regulation of urine volume
GO:0035815 positive regulation of renal sodium excretion
GO:0040013 negative regulation of locomotion
GO:0042311 vasodilation
GO:0042493 response to drug
GO:0042755 eating behavior
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043116 negative regulation of vascular permeability
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0044267 cellular protein metabolic process
GO:0044877 protein-containing complex binding
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep
GO:0048143 astrocyte activation
GO:0048786 presynaptic active zone
GO:0048812 neuron projection morphogenesis
GO:0050714 positive regulation of protein secretion
GO:0051393 alpha-actinin binding
GO:0051881 regulation of mitochondrial membrane potential
GO:0051899 membrane depolarization
GO:0051924 regulation of calcium ion transport
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0060079 excitatory postsynaptic potential
GO:0060134 prepulse inhibition
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:1900273 positive regulation of long-term synaptic potentiation
GO:2000300 regulation of synaptic vesicle exocytosis

Diseases

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Interactions

33 interactions

InteractorPartnerSourcesPublicationsLink
ADORA2ANAMPTBioGRID, MINT18486613 details
ADORA2AADORA2ABioGRID, HPRD, IntAct, MINT12804599 12837758 18675812 19013155 29568380 details
ADORA2ACYTH2BioGRID, HPRD, IntAct16027149 details
ADORA2AADORA1IntAct16481441 details
ADORA2ANECAB2BioGRID, IntAct, UniProt17689978 19694902 details
ADORA2ACNR1BioGRID, I2D, IntAct17356572 23296780 28102227 details
ADORA2AUSP4I2D16339847 details
ADORA2ACALM1I2D19632986 details
ADORA2ACALM2I2D19632986 details
ADORA2ACALM3I2D19632986 details
ADORA2ADRD2BioGRID, HPRD, I2D, IntAct12804599 19632986 23296780 29568380 details
ADORA2ASYNGR1BioGRID, IntAct32296183 details
ADORA2ABET1BioGRID, IntAct32296183 details
ADORA2AGPR37BioGRID, MINT28298427 details
ADORA2ACHN1BioGRID, MINT28298427 details
ADORA2AHNRNPH3BioGRID, MINT28298427 details
ADORA2APOMZP3BioGRID, MINT28298427 details
ADORA2APPM1JBioGRID, MINT28298427 details
ADORA2APDHBBioGRID, MINT28298427 details
ADORA2ARHBDD2BioGRID, MINT28298427 details
ADORA2ASLC25A39BioGRID, MINT28298427 details
ADORA2ASLC4A1APBioGRID, MINT28298427 details
ADORA2ASPNS1BioGRID, MINT28298427 details
ADORA2AADORA2BIntAct29568380 details
ADORA2AHRH3BioGRID29217157 details
ADORA2ACD4BioGRID17356572 details
ADORA2AACTN4HPRD12837758 details
ADORA2AACTN1HPRD12837758 details
ADORA2AACTN3HPRD12837758 details
ADORA2AWLSUniProt28734904 31286866 details
ADORA2AADABioGRID, HPRD11125033 details
ADORA2AGRM5BioGRID12189203 details
ADORA2AACTN2HPRD12837758 details