Entity Details

Primary name ULA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13564
EntryNameULA1_HUMAN
FullNameNEDD8-activating enzyme E1 regulatory subunit
TaxID9606
Evidenceevidence at protein level
Length534
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesNAE1

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0019781 NEDD8 activating enzyme activity
GO:0031625 ubiquitin protein ligase binding
GO:0032446 protein modification by small protein conjugation
GO:0032991 protein-containing complex
GO:0033314 mitotic DNA replication checkpoint signaling
GO:0042981 regulation of apoptotic process
GO:0043523 regulation of neuron apoptotic process
GO:0043687 post-translational protein modification
GO:0045116 protein neddylation
GO:0046982 protein heterodimerization activity
GO:0051402 neuron apoptotic process

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000594 THIF-type NAD/FAD binding foldDomainDomain
IPR030667 NEDD8-activating enzyme E1 regulatory subunit APP-BP1FamilyFamily
IPR035985 Ubiquitin-activating enzymeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00171 ATPDrugbanksmall molecule