Entity Details

Primary name LAPM5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13571
EntryNameLAPM5_HUMAN
FullNameLysosomal-associated transmembrane protein 5
TaxID9606
Evidenceevidence at protein level
Length262
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesLAPTM5

GO terms

Show/Hide Table
GOName
GO:0002357 defense response to tumor cell
GO:0002720 positive regulation of cytokine production involved in immune response
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005887 integral component of plasma membrane
GO:0006622 protein targeting to lysosome
GO:0006886 intracellular protein transport
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0012502 induction of programmed cell death
GO:0030133 transport vesicle
GO:0031398 positive regulation of protein ubiquitination
GO:0031410 cytoplasmic vesicle
GO:0031625 ubiquitin protein ligase binding
GO:0032689 negative regulation of interferon-gamma production
GO:0032703 negative regulation of interleukin-2 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032991 protein-containing complex
GO:0043410 positive regulation of MAPK cascade
GO:0048471 perinuclear region of cytoplasm
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0050868 negative regulation of T cell activation
GO:0050869 negative regulation of B cell activation
GO:0060907 positive regulation of macrophage cytokine production
GO:0090160 Golgi to lysosome transport
GO:0097214 positive regulation of lysosomal membrane permeability
GO:0140036 ubiquitin-dependent protein binding
GO:0140311 protein sequestering activity
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway
GO:1904093 negative regulation of autophagic cell death
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process
GO:2000646 positive regulation of receptor catabolic process

Subcellular Location

Show/Hide Table
Subcellular Location
Lysosome membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR004687 Lysosomal-associated transmembrane protein 4/5FamilyFamily
IPR018396 Lysosomal-associated transmembrane protein, 4A/5FamilyFamily
IPR018397 Lysosomal-associated transmembrane protein 5FamilyFamily

Diseases

Show/Hide Table

Interactions

41 interactions

InteractorPartnerSourcesPublicationsLink
LAPM5_HUMANUB2J1_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANHMOX2_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANVAMP1_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANAN13A_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANWWP1_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANDISP1_HUMANBioGRID, IntAct25416956 details
LAPM5_HUMANGLPA_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANEPN3_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANRL40_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANEPN2_HUMANHPRD15231748 details
LAPM5_HUMANDCNL1_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANNB5R3_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANUBP13_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANEPN1_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANHEY1_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANNEDD4_HUMANBioGRID, MINT15231748 17116753 19953087 details
LAPM5_HUMANCLD19_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANCD003_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANS22A2_HUMANBioGRID31318583 details
LAPM5_HUMANTNAP3_HUMANBioGRID, HPRD, MINT15231748 22733818 details
LAPM5_HUMANNED4L_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANTM1L2_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANLRAD1_HUMANBioGRID, IntAct25416956 details
LAPM5_HUMANUBAC1_HUMANHPRD15231748 details
LAPM5_HUMANK2C7_HUMANHPRD15231748 details
LAPM5_HUMANAIG1_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANRM18_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANRTP2_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANSMUF2_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANUBC_HUMANBioGRID17116753 details
LAPM5_HUMANHEYL_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANINSI2_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANHUWE1_HUMANHPRD15231748 details
LAPM5_HUMANRN168_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANEPS15_HUMANBioGRID, HPRD, MINT15231748 details
LAPM5_HUMANKI3L3_HUMANIntAct32296183 details
LAPM5_HUMANITCH_HUMANBioGRID22009753 details
LAPM5_HUMANRPRM_HUMANBioGRID, IntAct32296183 details
LAPM5_HUMANHERC1_HUMANHPRD15231748 details
LAPM5_HUMANLAMP1_HUMANBioGRID22733818 details
LAPM5_HUMANGGA3_HUMANBioGRID17116753 details