Entity Details

Primary name MECOM
Entity type gene
Source Source Link

Details

PrimaryID2122
RefseqGeneNG_028279
SymbolMECOM
NameMDS1 and EVI1 complex locus
Chromosome3
Location3q26.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1990-07-17
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMECOM_HUMAN

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006915 apoptotic process
GO:0016607 nuclear speck
GO:0030154 cell differentiation
GO:0042803 protein homodimerization activity
GO:0043069 negative regulation of programmed cell death
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046329 negative regulation of JNK cascade
GO:0046872 metal ion binding
GO:0046974 histone methyltransferase activity (H3-K9 specific)
GO:0051726 regulation of cell cycle
GO:0070828 heterochromatin organization
GO:0071425 hematopoietic stem cell proliferation

Diseases

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Interactions

225 interactions

InteractorPartnerSourcesPublicationsLink
MECOMUXTIntAct17635584 details
MECOMPRMT1BioGRID, MINT23455924 details
MECOMPIK3R3BioGRID, IntAct25814554 details
MECOMRABGAP1LBioGRID, IntAct25814554 details
MECOMCLIC3BioGRID, IntAct32296183 details
MECOMCTBP1BioGRID, HPRD, IntAct11313276 11328817 11568182 26186194 28514442 30462309 details
MECOMRBBP4BioGRID, MINT30462309 details
MECOMAPBB2IntAct32814053 details
MECOMHSPB1BioGRID, IntAct30462309 32814053 details
MECOMWFS1IntAct32814053 details
MECOMKIF1BIntAct32814053 details
MECOMRNF11IntAct32814053 details
MECOMHDAC1BioGRID, HPRD11552981 11568182 30462309 details
MECOMCREBBPBioGRID, HPRD11568182 details
MECOMKAT2BBioGRID, HPRD11568182 20363750 details
MECOMSMAD3BioGRID, HPRD15849193 9665135 details
MECOMMBD3BioGRID18500823 30462309 details
MECOMSUV39H1BioGRID18619962 18655152 details
MECOMSMAD1BioGRID15849193 details
MECOMSMAD2BioGRID15849193 details
MECOMSMAD4BioGRID15849193 details
MECOMUBE2IBioGRID23770046 details
MECOMHIC1BioGRID24907396 details
MECOMMECOMBioGRID, HPRD14603251 30462309 details
MECOMSIRT1BioGRID, UniProt21555002 details
MECOMFOSDIP22308434 details
MECOMHDAC4BioGRID, HPRD11568182 details
MECOMEHMT2BioGRID18619962 details
MECOMPIAS4BioGRID23770046 details
MECOMCTBP2BioGRID, HPRD30462309 9724649 details
MECOMMTA1BioGRID30462309 details
MECOMHDAC2BioGRID30462309 details
MECOMSMG7BioGRID29395067 details
MECOMERMAPBioGRID, IntAct28514442 details
MECOML3MBTL1BioGRID, IntAct28514442 details
MECOMSPDEFBioGRID, IntAct26186194 28514442 details
MECOMJUNBDIP22308434 details
MECOMJUNDIP22308434 details
MECOMFOSL2DIP22308434 details
MECOMFOSBDIP22308434 details
MECOMYY1DIP22308434 details
MECOMMED23BioGRID, MINT25281560 details
MECOMCHCHD2BioGRID, MINT24981860 details
MECOMAPPBP2BioGRID, MINT24981860 details
MECOMMYCBPBioGRID, MINT24981860 details
MECOMSOX2BioGRID, MINT23667531 details
MECOMNLRP14BioGRID26344197 details
MECOMFOXJ2BioGRID25609649 details
MECOMCHD3BioGRID28977666 details
MECOMCHD4BioGRID30462309 details
MECOMCSNK2A1BioGRID30462309 details
MECOMSLC25A13BioGRID30462309 details
MECOMATP5PBBioGRID30462309 details
MECOMTBL3BioGRID30462309 details
MECOMSONBioGRID30462309 details
MECOMPFKLBioGRID30462309 details
MECOMMAP1BBioGRID30462309 details
MECOMATP2A2BioGRID30462309 details
MECOMSLC25A11BioGRID30462309 details
MECOMMAGED2BioGRID30462309 details
MECOMATP5POBioGRID30462309 details
MECOMIQGAP3BioGRID30462309 details
MECOMCYFIP1BioGRID30462309 details
MECOMDNAJA3BioGRID30462309 details
MECOMLBRBioGRID30462309 details
MECOMNCAPHBioGRID30462309 details
MECOMABCF2BioGRID30462309 details
MECOMEIF3LBioGRID30462309 details
MECOMRPS27ABioGRID30462309 details
MECOMMYO1BBioGRID30462309 details
MECOMNUP160BioGRID30462309 details
MECOMNDUFA9BioGRID30462309 details
MECOMNAP1L1BioGRID30462309 details
MECOMSAMHD1BioGRID30462309 details
MECOMDDX49BioGRID30462309 details
MECOMPDHBBioGRID30462309 details
MECOMCYC1BioGRID30462309 details
MECOMAHCTF1BioGRID30462309 details
MECOMAP2M1BioGRID30462309 details
MECOMDDX24BioGRID30462309 details
MECOMPSMC5BioGRID30462309 details
MECOMDDX27BioGRID30462309 details
MECOMNOC3LBioGRID30462309 details
MECOMCIAO2BBioGRID30462309 details
MECOMWDR74BioGRID30462309 details
MECOMPPP2CABioGRID30462309 details
MECOMCOX5ABioGRID30462309 details
MECOMLGALS3BPBioGRID30462309 details
MECOMSMC1ABioGRID30462309 details
MECOMAKAP8LBioGRID30462309 details
MECOMCCT6ABioGRID30462309 details
MECOMNUP133BioGRID30462309 details
MECOMPSMC4BioGRID30462309 details
MECOMARHGEF2BioGRID30462309 details
MECOMUTP4BioGRID30462309 details
MECOMRBFOX2BioGRID30462309 details
MECOMRHEBBioGRID30462309 details
MECOMKPNA2BioGRID30462309 details
MECOMFXR2BioGRID30462309 details
MECOMPSMC6BioGRID30462309 details
MECOMPHF6BioGRID30462309 details
MECOMRBM15BioGRID30462309 details
MECOMGRWD1BioGRID30462309 details
MECOMPHGDHBioGRID30462309 details
MECOMMAP7D1BioGRID30462309 details
MECOMSRSF6BioGRID30462309 details
MECOMKPNB1BioGRID30462309 details
MECOMNCAPD2BioGRID30462309 details
MECOMHAX1BioGRID30462309 details
MECOMZCCHC8BioGRID30462309 details
MECOMPAF1BioGRID30462309 details
MECOMCOPG1BioGRID30462309 details
MECOMABCD3BioGRID30462309 details
MECOMCSNK2BBioGRID30462309 details
MECOMPSMD3BioGRID30462309 details
MECOMRFC1BioGRID30462309 details
MECOMHADHABioGRID30462309 details
MECOMTUBB6BioGRID30462309 details
MECOMH3C1BioGRID30462309 details
MECOMRBM14BioGRID30462309 details
MECOMCBX3BioGRID30462309 details
MECOMRBM39BioGRID30462309 details
MECOMDNAJB6BioGRID30462309 details
MECOMRPL5BioGRID30462309 details
MECOMEIF3EBioGRID30462309 details
MECOMPSMC1BioGRID30462309 details
MECOMSNRPD1BioGRID30462309 details
MECOMAKAP8BioGRID30462309 details
MECOMTIMM44BioGRID30462309 details
MECOMEIF3CBioGRID30462309 details
MECOMRTRAFBioGRID30462309 details
MECOMTHOC2BioGRID30462309 details
MECOMCLTCBioGRID30462309 details
MECOMKHDRBS1BioGRID30462309 details
MECOMTUBA1ABioGRID30462309 details
MECOMPSMC2BioGRID30462309 details
MECOMRPS15BioGRID30462309 details
MECOMDDX17BioGRID30462309 details
MECOMFTSJ3BioGRID30462309 details
MECOMACTR2BioGRID30462309 details
MECOMTIMM50BioGRID30462309 details
MECOMNOP56BioGRID30462309 details
MECOMAP1M1BioGRID30462309 details
MECOMH3C14BioGRID30462309 details
MECOMRPN1BioGRID30462309 details
MECOMEIF3DBioGRID30462309 details
MECOMRCN2BioGRID30462309 details
MECOMP4HA1BioGRID30462309 details
MECOMCDC5LBioGRID30462309 details
MECOMATP1A1BioGRID30462309 details
MECOMCOPB1BioGRID30462309 details
MECOMPPP6R3BioGRID30462309 details
MECOMNAT10BioGRID30462309 details
MECOMNUP93BioGRID30462309 details
MECOMHNRNPH1BioGRID26760575 30462309 details
MECOMTUFMBioGRID30462309 details
MECOMPFKPBioGRID30462309 details
MECOMCOPABioGRID30462309 details
MECOMPRKDCBioGRID30462309 details
MECOMNUP205BioGRID30462309 details
MECOMSSRP1BioGRID30462309 details
MECOMCOPEBioGRID30462309 details
MECOMDHX15BioGRID30462309 details
MECOMSUPT16HBioGRID30462309 details
MECOMBAG2BioGRID30462309 details
MECOMSLC3A2BioGRID30462309 details
MECOMHP1BP3BioGRID30462309 details
MECOMCAVIN1BioGRID30462309 details
MECOMSUCLG2BioGRID30462309 details
MECOMALDH1B1BioGRID30462309 details
MECOMMTREXBioGRID30462309 details
MECOMRRS1BioGRID30462309 details
MECOMSRSF9BioGRID30462309 details
MECOMUQCRHBioGRID30462309 details
MECOMSQSTM1BioGRID30462309 details
MECOMRPS26BioGRID30462309 details
MECOMACADMBioGRID30462309 details
MECOMYBX3BioGRID30462309 details
MECOMRPS7BioGRID30462309 details
MECOMCTPS1BioGRID30462309 details
MECOMHNRNPUL2BioGRID30462309 details
MECOMSRSF1BioGRID30462309 details
MECOMRPN2BioGRID30462309 details
MECOMMATR3BioGRID30462309 details
MECOMDDX3XBioGRID30462309 details
MECOMTCP1BioGRID30462309 details
MECOMMCM7BioGRID30462309 details
MECOMCALUBioGRID30462309 details
MECOMHNRNPFBioGRID30462309 details
MECOMFLNCBioGRID30462309 details
MECOMMYO1CBioGRID30462309 details
MECOMMTA2BioGRID30462309 details
MECOMGATAD2BBioGRID30462309 details
MECOMGATAD2ABioGRID30462309 details
MECOMDNAJC9BioGRID30462309 details
MECOMPLRG1BioGRID30462309 details
MECOMH1-2BioGRID30462309 details
MECOMPUM3BioGRID30462309 details
MECOMIQGAP1BioGRID30462309 details
MECOMSART1BioGRID30462309 details
MECOMTP53BioGRID30462309 details
MECOMHNRNPABBioGRID30462309 details
MECOMPNNBioGRID30462309 details
MECOMRBBP7BioGRID30462309 details
MECOMDDX47BioGRID30462309 details
MECOMGTPBP4BioGRID30462309 details
MECOMMYBBP1ABioGRID30462309 details
MECOMBAZ1BBioGRID30462309 details
MECOMPSIP1BioGRID30462309 details
MECOMMACROH2A1BioGRID30462309 details
MECOMDKC1BioGRID30462309 details
MECOMGNL2BioGRID30462309 details
MECOMACTR1ABioGRID30462309 details
MECOMGNL3BioGRID30462309 details
MECOMNOP58BioGRID30462309 details
MECOMSYNCRIPBioGRID30462309 details
MECOMPRPF19BioGRID30462309 details
MECOMH4C1BioGRID30804502 details
MECOMPHIPBioGRID31753913 details
MECOMTRIM37BioGRID32908313 details
MECOMCENPABioGRID34079125 details
MECOMELAVL1BioGRID19322201 details
MECOMTNIP2BioGRID27609421 details
MECOMVIRMABioGRID29507755 details
MECOMAPEX1BioGRID28986522 details