Entity Details

Primary name FGA
Entity type gene
Source Source Link

Details

PrimaryID2243
RefseqGeneNG_008832
SymbolFGA
Namefibrinogen alpha chain
Chromosome4
Location4q31.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsFIBA_HUMAN

GO terms

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GOName
GO:0002224 toll-like receptor signaling pathway
GO:0002250 adaptive immune response
GO:0002576 platelet degranulation
GO:0005102 signaling receptor binding
GO:0005198 structural molecule activity
GO:0005201 extracellular matrix structural constituent
GO:0005576 extracellular region
GO:0005577 fibrinogen complex
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0007160 cell-matrix adhesion
GO:0007596 blood coagulation
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0030198 extracellular matrix organization
GO:0031091 platelet alpha granule
GO:0031093 platelet alpha granule lumen
GO:0031639 plasminogen activation
GO:0034116 positive regulation of heterotypic cell-cell adhesion
GO:0034622 cellular protein-containing complex assembly
GO:0042730 fibrinolysis
GO:0043152 induction of bacterial agglutination
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0045087 innate immune response
GO:0045202 synapse
GO:0045907 positive regulation of vasoconstriction
GO:0045921 positive regulation of exocytosis
GO:0046872 metal ion binding
GO:0050714 positive regulation of protein secretion
GO:0051258 protein polymerization
GO:0051592 response to calcium ion
GO:0062023 collagen-containing extracellular matrix
GO:0065003 protein-containing complex assembly
GO:0070062 extracellular exosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070527 platelet aggregation
GO:0072377 blood coagulation, common pathway
GO:0072378 blood coagulation, fibrin clot formation
GO:0072562 blood microparticle
GO:0090277 positive regulation of peptide hormone secretion
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1903561 extracellular vesicle
GO:1990000 amyloid fibril formation
GO:2000261 negative regulation of blood coagulation, common pathway
GO:2000352 negative regulation of endothelial cell apoptotic process

Diseases

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Interactions

60 interactions

InteractorPartnerSourcesPublicationsLink
FGAPRRC2ABioGRID, HPRD, IntAct14667819 details
FGAKRT18IntAct10954706 details
FGAKLK6IntAct12878203 details
FGAPASKMINT21418524 details
FGATFIP11BioGRID, IntAct32296183 details
FGASH3BP1BioGRID, IntAct32296183 details
FGATMEM43BioGRID, IntAct32296183 details
FGAEXOC5BioGRID, IntAct32296183 details
FGASTX2BioGRID, IntAct32296183 details
FGATPM3BioGRID, IntAct32296183 details
FGATPM1BioGRID, IntAct32296183 details
FGASTX1BBioGRID, IntAct32296183 details
FGAFAM20CIntAct22582013 26091039 details
FGALAMP2IntAct32814053 details
FGASH3GLB1IntAct32814053 details
FGASOD1IntAct32814053 details
FGAPLATBioGRID, HPRD11170397 3088041 details
FGANID1BioGRID, HPRD1680863 details
FGAHRGBioGRID, HPRD9276466 details
FGATHBS1BioGRID, HPRD9867861 details
FGACDH5BioGRID, HPRD11900554 details
FGAUBCBioGRID23314748 details
FGAITGA2BBioGRID, HPRD11460491 9058485 details
FGAITGB3BioGRID, HPRD11460491 9058485 details
FGAMEOX2BioGRID26871637 details
FGAAGTRAPBioGRID26871637 details
FGAAPPBioGRID27221710 details
FGASYCE1LBioGRID32296183 details
FGALRP1BBioGRID21420681 details
FGAHSP90AA1BioGRID31273033 details
FGAF2BioGRID, HPRD, IntAct1587268 2133223 25241761 2742826 details
FGAF13A1BioGRID, HPRD10956659 details
FGAFGABioGRID, HPRD9689040 details
FGASERPINF2HPRD10963790 14751930 details
FGASERPINA5HPRD8384496 8589203 details
FGAFGBBioGRID, DIP, HPRD, IntAct12356313 14992584 18294856 21475196 25427968 details
FGAFGGBioGRID, DIP, HPRD, IntAct12356313 14992584 18294856 21475196 25427968 details
FGAAPOA1BioGRID, IntAct15174051 25241761 details
FGAALBBioGRID, IntAct15174051 details
FGAMIS12BioGRID, IntAct20360068 details
FGATRIM33BioGRID, IntAct26496610 details
FGASNX27BioGRID, IntAct28514442 details
FGADDX19BBioGRID, IntAct26186194 28514442 details
FGAALDH2BioGRID, IntAct26186194 28514442 details
FGAMAPK6BioGRID, IntAct28514442 details
FGAH2BC11BioGRID, IntAct28514442 details
FGARING1BioGRID, IntAct28514442 details
FGAYWHAQIntAct28514442 details
FGAPRNPBioGRID, UniProt29791485 details
FGAF13BIntAct31159152 details
FGAC1QBPIntAct28565870 details
FGANSD2BioGRID, MINT24981860 details
FGAKHDRBS2BioGRID17643375 details
FGAFN1BioGRID23750785 details
FGAASB6BioGRID24337577 details
FGAASB7BioGRID24337577 details
FGAESR2BioGRID29509190 details
FGAFANCD2BioGRID31180492 details
FGATRIM6BioGRID31992359 details
FGAMTIF2BioGRID32877691 details