Entity Details

Primary name SETX
Entity type gene
Source Source Link

Details

PrimaryID23064
RefseqGeneNG_007946
SymbolSETX
Namesenataxin
Chromosome9
Location9q34.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-30
ModificationDate2021-06-19

Ontological Relatives

UniProt IDsSETX_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000228 nuclear chromosome
GO:0000781 chromosome, telomeric region
GO:0001147 transcription termination site sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006302 double-strand break repair
GO:0006310 DNA recombination
GO:0006353 DNA-templated transcription, termination
GO:0006369 termination of RNA polymerase II transcription
GO:0006376 mRNA splice site selection
GO:0006396 RNA processing
GO:0006974 cellular response to DNA damage stimulus
GO:0007283 spermatogenesis
GO:0007399 nervous system development
GO:0007623 circadian rhythm
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010976 positive regulation of neuron projection development
GO:0016604 nuclear body
GO:0030154 cell differentiation
GO:0030424 axon
GO:0030426 growth cone
GO:0033120 positive regulation of RNA splicing
GO:0034599 cellular response to oxidative stress
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043491 protein kinase B signaling
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0045171 intercellular bridge
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060566 positive regulation of DNA-templated transcription, termination
GO:0070301 cellular response to hydrogen peroxide
GO:0071300 cellular response to retinoic acid
GO:2000144 positive regulation of DNA-templated transcription, initiation
GO:2000806 positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled

Diseases

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Interactions

79 interactions

InteractorPartnerSourcesPublicationsLink
SETXUBE2IBioGRID, IntAct, UniProt20936779 24244371 details
SETXTDGUniProt24244371 details
SETXTOPORSUniProt24244371 details
SETXEXOSC9UniProt24244371 details
SETXUBA2UniProt24244371 details
SETXSETXUniProt24244371 details
SETXPIAS1UniProt24244371 details
SETXCHD3UniProt24244371 details
SETXUBCUniProt24244371 details
SETXSUMO1BioGRID, UniProt16524884 24244371 details
SETXHIPK2UniProt24244371 details
SETXBRCA1BioGRID, UniProt25184681 25699710 29656893 details
SETXSAMD3IntAct32814053 details
SETXWDR61IntAct32814053 details
SETXUSP2IntAct32814053 details
SETXSUMO2BioGRID16524884 details
SETXPTENBioGRID26561776 details
SETXPOLR2ABioGRID, DIP26700805 details
SETXSMN1BioGRID, DIP26700805 details
SETXSMN2DIP26700805 details
SETXFAM120BBioGRID29968717 details
SETXAPOA1BioGRID, IntAct15174051 details
SETXALBBioGRID, IntAct15174051 details
SETXTFIntAct15174051 details
SETXSNW1MINT20467437 details
SETXCDC5LBioGRID, MINT20467437 details
SETXMYCBioGRID, IntAct21150319 29467282 details
SETXPTBP3MINT22575643 details
SETXMEF2ABioGRID, MINT25609649 details
SETXPOLR2FBioGRID, IntAct26496610 details
SETXCLUBioGRID, IntAct26496610 details
SETXPOLR2GBioGRID, IntAct26496610 details
SETXSUPT5HBioGRID, IntAct26496610 details
SETXCNTROBBioGRID, IntAct26496610 details
SETXNEUROG3BioGRID, IntAct28514442 details
SETXVWA5ABioGRID, IntAct28514442 details
SETXVIPR2BioGRID, IntAct28514442 details
SETXISLRBioGRID, IntAct26186194 28514442 details
SETXSIGLECL1BioGRID, IntAct28514442 details
SETXPNKDBioGRID, IntAct26186194 28514442 details
SETXCOMTD1BioGRID, IntAct26186194 28514442 details
SETXAPBB1BioGRID, IntAct28514442 details
SETXMAPK8IP1BioGRID, IntAct28514442 details
SETXFZD10BioGRID, IntAct28514442 details
SETXCD2APBioGRID, IntAct28514442 details
SETXVPS28BioGRID, IntAct28514442 details
SETXPAK1BioGRID, IntAct28514442 details
SETXARHGAP1BioGRID, IntAct28514442 details
SETXSETMARBioGRID, IntAct28514442 details
SETXPRMT5DIP26700805 details
SETXTP53BP1BioGRID, UniProt29656893 details
SETXPPIBBioGRID, IntAct30021884 details
SETXESR1BioGRID, IntAct31527615 details
SETXHNRNPH1MINT29725819 details
SETXMLST8BioGRID26186194 details
SETXSKAP1BioGRID26186194 details
SETXCARD8BioGRID26186194 details
SETXLCN15BioGRID26186194 details
SETXEGFRBioGRID28065597 details
SETXCDH19BioGRID28514442 details
SETXCYLDBioGRID27591049 details
SETXEGLN3BioGRID26972000 details
SETXESR2BioGRID29509190 details
SETXRNF123BioGRID29676528 details
SETXEZH2BioGRID27634302 details
SETXSUZ12BioGRID27634302 details
SETXH4C1BioGRID30804502 details
SETXPSMD14BioGRID30745168 details
SETXWWP2BioGRID31048545 details
SETXNIPBLBioGRID31010829 details
SETXMAU2BioGRID31010829 details
SETXCITBioGRID31586073 details
SETXAURKBBioGRID31586073 details
SETXKIF14BioGRID31586073 details
SETXKIF20ABioGRID31586073 details
SETXTERF2IPBioGRID34079125 details
SETXTRIM25BioGRID29117863 details
SETXVIRMABioGRID29507755 details
SETXDDX58BioGRID32513696 details