Entity Details

Primary name PSME4
Entity type gene
Source Source Link

Details

PrimaryID23198
RefseqGene
SymbolPSME4
Nameproteasome activator subunit 4
Chromosome2
Location2p16.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPSME4_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000209 protein polyubiquitination
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006521 regulation of cellular amino acid metabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007275 multicellular organism development
GO:0010499 proteasomal ubiquitin-independent protein catabolic process
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
GO:0016504 peptidase activator activity
GO:0016579 protein deubiquitination
GO:0016607 nuclear speck
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035093 spermatogenesis, exchange of chromosomal proteins
GO:0036388 pre-replicative complex assembly
GO:0038061 NIK/NF-kappaB signaling
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043488 regulation of mRNA stability
GO:0043687 post-translational protein modification
GO:0050852 T cell receptor signaling pathway
GO:0055085 transmembrane transport
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070577 lysine-acetylated histone binding
GO:0070628 proteasome binding
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1990111 spermatoproteasome complex

Diseases

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Interactions

58 interactions

InteractorPartnerSourcesPublicationsLink
PSME4H4C1BioGRID, IntAct23706739 32447347 details
PSME4CALCOCO2BioGRID, IntAct25416956 details
PSME4NUTM1BioGRID, IntAct25416956 details
PSME4MTNR1ABioGRID, IntAct26514267 details
PSME4FBXL17BioGRID31560077 details
PSME4H4-16IntAct23706739 details
PSME4H4C15IntAct23706739 details
PSME4H4C9IntAct23706739 details
PSME4H4C4IntAct23706739 details
PSME4H4C6IntAct23706739 details
PSME4H4C12IntAct23706739 details
PSME4H4C11IntAct23706739 details
PSME4H4C3IntAct23706739 details
PSME4H4C8IntAct23706739 details
PSME4H4C2IntAct23706739 details
PSME4H4C5IntAct23706739 details
PSME4H4C13IntAct23706739 details
PSME4H4C14IntAct23706739 details
PSME4PSMC6DIP18845680 details
PSME4RAD23ABioGRID19013454 details
PSME4PSMA2BioGRID19193609 22863883 details
PSME4PSMD14BioGRID17323924 28821611 details
PSME4UBE3ABioGRID22645313 30257870 details
PSME4MYCBioGRID, IntAct17314511 29467282 details
PSME4COPS5BioGRID, IntAct21145461 details
PSME4SEM1BioGRID, MINT24811749 details
PSME4JUNMINT25609649 details
PSME4SLX1ABioGRID, IntAct28514442 details
PSME4SLX1BIntAct28514442 details
PSME4PSMB9BioGRID, IntAct26186194 28514442 details
PSME4PSMB1BioGRID, IntAct22863883 28514442 details
PSME4PSMB4BioGRID, IntAct26186194 28514442 details
PSME4PSMB3BioGRID, IntAct22863883 28514442 details
PSME4PSMB2BioGRID, IntAct28514442 details
PSME4PSMB7BioGRID, IntAct26186194 28514442 details
PSME4TAF7LBioGRID, IntAct28514442 details
PSME4PSMA1BioGRID, IntAct26186194 26344197 28514442 details
PSME4A1BGBioGRID, IntAct28514442 details
PSME4KLHL10BioGRID, IntAct28514442 details
PSME4FDPSBioGRID, IntAct28514442 details
PSME4AMFRBioGRID, IntAct22119785 details
PSME4PSMA7BioGRID22863883 details
PSME4SEPTIN10BioGRID22863883 details
PSME4ARHGEF10BioGRID22863883 details
PSME4PSMA4BioGRID22863883 details
PSME4PSMA5BioGRID22863883 26344197 details
PSME4RUFY1BioGRID22863883 details
PSME4SART3BioGRID22863883 details
PSME4TTI1BioGRID22863883 details
PSME4DDX3XBioGRID26344197 details
PSME4PSMA3BioGRID26344197 details
PSME4PSMB6BioGRID26344197 details
PSME4PSMD3BioGRID26344197 details
PSME4NTRK1BioGRID25921289 details
PSME4PSME4BioGRID28292943 details
PSME4CUL4ABioGRID32235678 details
PSME4VIRMABioGRID29507755 details
PSME4HNRNPH1BioGRID26760575 details