Entity Details

Primary name KCJ12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14500
EntryNameKCJ12_HUMAN
FullNameATP-sensitive inward rectifier potassium channel 12
TaxID9606
Evidenceevidence at protein level
Length433
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesKCNJ12

GO terms

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GOName
GO:0005242 inward rectifier potassium channel activity
GO:0005886 plasma membrane
GO:0006813 potassium ion transport
GO:0006936 muscle contraction
GO:0008016 regulation of heart contraction
GO:0016021 integral component of membrane
GO:0031224 intrinsic component of membrane
GO:0034765 regulation of ion transmembrane transport
GO:0051289 protein homotetramerization
GO:0061337 cardiac conduction
GO:0071805 potassium ion transmembrane transport
GO:1901381 positive regulation of potassium ion transmembrane transport
GO:1990573 potassium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR003272 Potassium channel, inwardly rectifying, Kir2.2FamilyFamily
IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmicFamilyHomologous superfamily
IPR013673 Potassium channel, inwardly rectifying, Kir, N-terminalDomainDomain
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR016449 Potassium channel, inwardly rectifying, KirFamilyFamily
IPR040445 Potassium channel, inwardly rectifying, transmembrane domainDomainDomain
IPR041647 Inward rectifier potassium channel, C-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00204 DofetilideDrugbanksmall molecule
DB00243 RanolazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule
DB01392 YohimbineDrugbanksmall molecule
DB04855 DronedaroneDrugbanksmall molecule
DB11148 ButambenDrugbanksmall molecule