Entity Details

Primary name WWTR1
Entity type gene
Source Source Link

Details

PrimaryID25937
RefseqGene
SymbolWWTR1
NameWW domain containing transcription regulator 1
Chromosome3
Location3q25.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-14
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsWWTR1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001649 osteoblast differentiation
GO:0001894 tissue homeostasis
GO:0001933 negative regulation of protein phosphorylation
GO:0003015 heart process
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006469 negative regulation of protein kinase activity
GO:0007399 nervous system development
GO:0008284 positive regulation of cell population proliferation
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0016567 protein ubiquitination
GO:0016604 nuclear body
GO:0017145 stem cell division
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032835 glomerulus development
GO:0035264 multicellular organism growth
GO:0035329 hippo signaling
GO:0042803 protein homodimerization activity
GO:0045599 negative regulation of fat cell differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048762 mesenchymal cell differentiation
GO:0060271 cilium assembly
GO:0060390 regulation of SMAD protein signal transduction
GO:0060993 kidney morphogenesis
GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1900182 positive regulation of protein localization to nucleus

Diseases

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Interactions

63 interactions

InteractorPartnerSourcesPublicationsLink
WWTR1RUNX1HPRD, MINT11118213 details
WWTR1YWHAZBioGRID, MINT11118213 20936779 details
WWTR1TEAD4BioGRID, HPRD, I2D, IntAct16189514 20972459 25670202 26116754 26186194 28514442 30472188 31515488 32296183 details
WWTR1TEAD3BioGRID, HPRD, IntAct16189514 26186194 28514442 31515488 details
WWTR1MED28BioGRID, MINT16964398 details
WWTR1YWHAEBioGRID, HPRD, IntAct, MINT11118213 16099986 18227151 20936779 21189257 25961935 details
WWTR1YWHAGBioGRID, IntAct20936779 28514442 details
WWTR1WBP2BioGRID, I2D20972459 27578003 details
WWTR1LATS1bhf-ucl, BioGRID, IntAct20412773 21555462 22078877 26116754 27847303 29787761 details
WWTR1SCRIBIntAct22078877 30126976 details
WWTR1RTN4IntAct25416956 details
WWTR1TEAD2BioGRID, IntAct, MINT25609649 28514442 32296183 details
WWTR1TEAD1BioGRID, IntAct25796446 26186194 28514442 32296183 details
WWTR1IL16BioGRID, IntAct32296183 details
WWTR1TCP11L1BioGRID, IntAct32296183 details
WWTR1RTN4IP1BioGRID, IntAct32296183 details
WWTR1C1orf74BioGRID, IntAct32296183 details
WWTR1DAPK1BioGRID, IntAct29513927 details
WWTR1MFHAS1BioGRID, IntAct29513927 details
WWTR1SHANK1IntAct30126976 details
WWTR1SNTA1IntAct30126976 details
WWTR1PPP1CABioGRID21189257 26116754 details
WWTR1LATS2BioGRID25670202 details
WWTR1SUMO3BioGRID30472188 details
WWTR1USP10BioGRID32217697 details
WWTR1PRRG4BioGRID23873930 details
WWTR1PRRG2BioGRID23873930 details
WWTR1PAX3HPRD16300735 details
WWTR1SLC9A3R2BioGRID, HPRD, MINT11118213 details
WWTR1TJP1MINT20850437 details
WWTR1TJP2MINT20850437 details
WWTR1CCAR1Molecular Connections20594350 details
WWTR1WNK1IntAct20936779 details
WWTR1BTRCBioGRID, IntAct20412773 21189257 22078877 25900982 26091241 26116754 26186194 28018973 28514442 details
WWTR1CTNNB1IntAct, MINT22234184 23245942 details
WWTR1JUPIntAct23245942 details
WWTR1CCT2IntAct23245942 details
WWTR1DVL2bhf-ucl, BioGRID20412773 details
WWTR1DVL1bhf-ucl, BioGRID20412773 details
WWTR1DVL3bhf-ucl, BioGRID20412773 details
WWTR1DDX17IntAct24581491 details
WWTR1YWHAQBioGRID, IntAct21555462 28514442 details
WWTR1KLF5BioGRID22045023 details
WWTR1TP53BP2BioGRID21189257 details
WWTR1HIF1ABioGRID25447306 details
WWTR1HDAC9BioGRID25760078 details
WWTR1OTUB2BioGRID30472188 details
WWTR1DCAF12BioGRID31857346 details
WWTR1NKX2-1HPRD14970209 details
WWTR1NUDT21I2D20972459 details
WWTR1AMOTBioGRID, I2D20972459 26186194 details
WWTR1YBX1I2D20972459 details
WWTR1AMOTL1BioGRID, I2D20972459 26186194 details
WWTR1STK3IntAct22078877 details
WWTR1AXIN1IntAct24976009 details
WWTR1YAP1IntAct24976009 details
WWTR1NOTCH1BioGRID, MINT23022380 details
WWTR1YWHAHIntAct28514442 details
WWTR1FBXW11BioGRID26186194 details
WWTR1H4C1BioGRID30804502 details
WWTR1TRIM25BioGRID29117863 details
WWTR1APEX1BioGRID28986522 details
WWTR1USP39BioGRID31332287 details