Entity Details

Primary name HEYL
Entity type gene
Source Source Link

Details

PrimaryID26508
RefseqGene
SymbolHEYL
Namehes related family bHLH transcription factor with YRPW motif like
Chromosome1
Location1p34.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHEYL_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003151 outflow tract morphogenesis
GO:0003180 aortic valve morphogenesis
GO:0003181 atrioventricular valve morphogenesis
GO:0003184 pulmonary valve morphogenesis
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003203 endocardial cushion morphogenesis
GO:0003208 cardiac ventricle morphogenesis
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007219 Notch signaling pathway
GO:0007221 positive regulation of transcription of Notch receptor target
GO:0008134 transcription factor binding
GO:0009952 anterior/posterior pattern specification
GO:0010629 negative regulation of gene expression
GO:0014031 mesenchymal cell development
GO:0032835 glomerulus development
GO:0035914 skeletal muscle cell differentiation
GO:0042803 protein homodimerization activity
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045666 positive regulation of neuron differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050683 AF-1 domain binding
GO:0050767 regulation of neurogenesis
GO:0060317 cardiac epithelial to mesenchymal transition
GO:0060412 ventricular septum morphogenesis
GO:0060766 negative regulation of androgen receptor signaling pathway
GO:0061314 Notch signaling involved in heart development
GO:0071773 cellular response to BMP stimulus
GO:0072014 proximal tubule development

Diseases

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Interactions

25 interactions

InteractorPartnerSourcesPublicationsLink
HEYLZNF512BBioGRID, MINT15231748 details
HEYLSKILBioGRID, HPRD, MINT15231748 details
HEYLSMAD3BioGRID, HPRD, MINT15231748 details
HEYLHIPK3BioGRID, HPRD, MINT15231748 details
HEYLSMAD7BioGRID, HPRD, MINT15231748 details
HEYLATF7IPHPRD, MINT15231748 details
HEYLSMAD9BioGRID, HPRD, MINT15231748 details
HEYLLAPTM5BioGRID, HPRD, MINT15231748 details
HEYLPPP1CABioGRID, HPRD, MINT15231748 details
HEYLRBPMSBioGRID, HPRD, IntAct16189514 25416956 details
HEYLMDFIBioGRID, IntAct, MINT21516116 25416956 32296183 details
HEYLATXN1BioGRID, IntAct23275563 details
HEYLHTTBioGRID, IntAct23275563 details
HEYLRPGRIP1BioGRID, IntAct25416956 details
HEYLBANPBioGRID, IntAct32296183 details
HEYLKRTAP6-2BioGRID, IntAct32296183 details
HEYLPLEKHB2BioGRID, IntAct32296183 details
HEYLSP8BioGRID, IntAct20211142 details
HEYLHAND1BioGRID, HPRD10924525 details
HEYLAPPBioGRID21832049 details
HEYLHAND2HPRD10924525 details
HEYLFBXO45BioGRID26068074 details
HEYLPGGT1BBioGRID, IntAct26186194 28514442 details
HEYLARL10BioGRID, IntAct26186194 28514442 details
HEYLFNTABioGRID, IntAct26186194 28514442 details