Entity Details

Primary name KANK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14678
EntryNameKANK1_HUMAN
FullNameKN motif and ankyrin repeat domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length1352
SequenceStatuscomplete
DateCreated2003-08-29
DateModified2021-06-02

Ontological Relatives

GenesKANK1

GO terms

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GOName
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0008013 beta-catenin binding
GO:0008283 cell population proliferation
GO:0010977 negative regulation of neuron projection development
GO:0030036 actin cytoskeleton organization
GO:0030177 positive regulation of Wnt signaling pathway
GO:0030336 negative regulation of cell migration
GO:0030837 negative regulation of actin filament polymerization
GO:0032587 ruffle membrane
GO:0035023 regulation of Rho protein signal transduction
GO:0035024 negative regulation of Rho protein signal transduction
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0090303 positive regulation of wound healing
GO:0090521 glomerular visceral epithelial cell migration
GO:1900025 negative regulation of substrate adhesion-dependent cell spreading
GO:1900028 negative regulation of ruffle assembly
GO:2000114 regulation of establishment of cell polarity
GO:2000393 negative regulation of lamellipodium morphogenesis

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR002110 Ankyrin repeatRepeatRepeat
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR021939 Kank N-terminal motifSiteConserved site
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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