Entity Details

Primary name HGF
Entity type gene
Source Source Link

Details

PrimaryID3082
RefseqGeneNG_016274
SymbolHGF
Namehepatocyte growth factor
Chromosome7
Location7q21.11
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-17
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsHGF_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000187 obsolete activation of MAPK activity
GO:0000278 mitotic cell cycle
GO:0000902 cell morphogenesis
GO:0001837 epithelial to mesenchymal transition
GO:0001889 liver development
GO:0001934 positive regulation of protein phosphorylation
GO:0002576 platelet degranulation
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0008083 growth factor activity
GO:0010507 negative regulation of autophagy
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0030212 hyaluronan metabolic process
GO:0030335 positive regulation of cell migration
GO:0031093 platelet alpha granule lumen
GO:0031100 animal organ regeneration
GO:0031643 positive regulation of myelination
GO:0032715 negative regulation of interleukin-6 production
GO:0032733 positive regulation of interleukin-10 production
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0035729 cellular response to hepatocyte growth factor stimulus
GO:0042056 chemoattractant activity
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044877 protein-containing complex binding
GO:0045669 positive regulation of osteoblast differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048012 hepatocyte growth factor receptor signaling pathway
GO:0050673 epithelial cell proliferation
GO:0050728 negative regulation of inflammatory response
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051450 myoblast proliferation
GO:0051897 positive regulation of protein kinase B signaling
GO:0060326 cell chemotaxis
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0070572 positive regulation of neuron projection regeneration
GO:0090201 negative regulation of release of cytochrome c from mitochondria
GO:1900744 regulation of p38MAPK cascade
GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902947 regulation of tau-protein kinase activity
GO:2000573 positive regulation of DNA biosynthetic process

Diseases

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Interactions

41 interactions

InteractorPartnerSourcesPublicationsLink
HGFMETBioGRID, DIP, HPRD, IntAct15167892 16537482 1655405 17804794 17981115 1846706 18495663 18593464 19433454 20624990 22897854 28205554 8380735 details
HGFHGFBioGRID, DIP, HPRD, IntAct11597998 12051906 17804794 20624990 22897854 9817840 9886295 details
HGFSRPX2IntAct22242148 details
HGFMEOX2BioGRID, IntAct25416956 details
HGFADAMTSL4BioGRID, IntAct25416956 details
HGFHGFACDIP, HPRD20004165 8631970 details
HGFCLEC3BBioGRID, HPRD12694198 details
HGFSDC2BioGRID, HPRD8157651 details
HGFSDC1BioGRID, HPRD11830493 details
HGFBRCA1BioGRID25184681 details
HGFEPHA2BioGRID28205554 details
HGFLATS2BioGRID28205554 details
HGFMYCBioGRID28205554 details
HGFSTK11BioGRID28205554 details
HGFMAP2K5BioGRID28205554 details
HGFARNTBioGRID28205554 details
HGFCCND2BioGRID28205554 details
HGFCDK4BioGRID28205554 details
HGFCDK6BioGRID28205554 details
HGFCDKN2ABioGRID28205554 details
HGFCDKN2BBioGRID28205554 details
HGFERBB2BioGRID28205554 details
HGFFGFR4BioGRID28205554 details
HGFGLIS2BioGRID28205554 details
HGFMDM4BioGRID28205554 details
HGFNF2BioGRID28205554 details
HGFPDGFRABioGRID28205554 details
HGFRAF1BioGRID28205554 details
HGFTEAD2BioGRID28205554 details
HGFMAP2K6BioGRID28205554 details
HGFYWHAGBioGRID28205554 details
HGFFN1BioGRID, HPRD, IntAct15717924 25241761 details
HGFHPNHPRD15792801 details
HGFPLAUHPRD1334458 details
HGFVTNHPRD15717924 details
HGFLCN2HPRD15637066 details
HGFKLKB1HPRD10962009 12372819 details
HGFST14HPRD10962009 12372819 details
HGFF11HPRD10962009 12372819 details
HGFCD44IntAct22897854 details
HGFFKBP7BioGRID, IntAct26186194 28514442 details