Entity Details

Primary name IGFBP3
Entity type gene
Source Source Link

Details

PrimaryID3486
RefseqGeneNG_011508
SymbolIGFBP3
Nameinsulin like growth factor binding protein 3
Chromosome7
Location7p12.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-12-04
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsIBP3_HUMAN

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0001649 osteoblast differentiation
GO:0001933 negative regulation of protein phosphorylation
GO:0001968 fibronectin binding
GO:0005520 insulin-like growth factor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005788 endoplasmic reticulum lumen
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0008160 protein tyrosine phosphatase activator activity
GO:0008285 negative regulation of cell population proliferation
GO:0009968 negative regulation of signal transduction
GO:0010906 regulation of glucose metabolic process
GO:0014912 negative regulation of smooth muscle cell migration
GO:0016942 insulin-like growth factor binding protein complex
GO:0031994 insulin-like growth factor I binding
GO:0031995 insulin-like growth factor II binding
GO:0042567 insulin-like growth factor ternary complex
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043410 positive regulation of MAPK cascade
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0044342 type B pancreatic cell proliferation
GO:0045663 positive regulation of myoblast differentiation
GO:0046872 metal ion binding
GO:0048662 negative regulation of smooth muscle cell proliferation

Diseases

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Interactions

62 interactions

InteractorPartnerSourcesPublicationsLink
IGFBP3GTF3C1BioGRID, HPRD, IntAct16169070 details
IGFBP3POLA2BioGRID, HPRD, IntAct16169070 details
IGFBP3AURKABioGRID, MINT24412244 details
IGFBP3BMPR1ABioGRID, MINT24412244 details
IGFBP3BUB1BioGRID, MINT24412244 details
IGFBP3CCND1BioGRID, MINT24412244 details
IGFBP3FBXW7BioGRID, MINT24412244 details
IGFBP3KRASBioGRID, MINT24412244 details
IGFBP3MLH3BioGRID, MINT24412244 details
IGFBP3RAD54BBioGRID, MINT24412244 details
IGFBP3STK11BioGRID, MINT24412244 details
IGFBP3FAM20CIntAct26091039 details
IGFBP3IGF1BioGRID, DIP, HPRD10823924 11600567 12735930 1383255 22578544 9446566 9497324 details
IGFBP3IGF2BioGRID, DIP, HPRD10407151 11600567 11749962 22578544 9446566 9497324 details
IGFBP3TMEM219IntAct20353938 details
IGFBP3CD44BioGRID, HPRD, UniProt12127836 30184438 details
IGFBP3PRKCAIntAct32814053 details
IGFBP3YWHAGIntAct32814053 details
IGFBP3SETDB1IntAct32814053 details
IGFBP3KAT5IntAct32814053 details
IGFBP3LMO3IntAct32814053 details
IGFBP3COL1A1BioGRID, HPRD12735930 details
IGFBP3PLGBioGRID, HPRD7538844 8843739 9337997 9688635 details
IGFBP3FN1BioGRID, HPRD11344214 12127836 details
IGFBP3ADAM12BioGRID, HPRD10849447 11095942 details
IGFBP3PAPPA2BioGRID, HPRD11264294 details
IGFBP3TFBioGRID, HPRD11297622 11749962 details
IGFBP3RXRABioGRID, HPRD10874028 details
IGFBP3IGFALSBioGRID, HPRD9446566 9497324 details
IGFBP3LTBP1BioGRID, HPRD12962157 details
IGFBP3PPARGBioGRID25449421 details
IGFBP3NONOBioGRID30725116 details
IGFBP3PRKDCIntAct23178489 details
IGFBP3EGFRIntAct23178489 details
IGFBP3IGF1RBioGRID, HPRD9389554 details
IGFBP3SFPQBioGRID30725116 details
IGFBP3CSNK2A1HPRD10650937 details
IGFBP3CTSGHPRD10512690 details
IGFBP3CTSDHPRD9275067 details
IGFBP3CTSLHPRD11801256 details
IGFBP3GPIHPRD15059907 details
IGFBP3MMP1HPRD7523391 details
IGFBP3MMP2HPRD7523391 details
IGFBP3CAV1HPRD14576164 details
IGFBP3F2HPRD7538844 8843739 details
IGFBP3KLK3HPRD10218588 7538844 details
IGFBP3MMP3HPRD7523391 details
IGFBP3KLKB1HPRD10226805 details
IGFBP3KPNB1HPRD10811646 details
IGFBP3IGFBP3UniProt30184438 details
IGFBP3KRT19BioGRID30725116 details
IGFBP3ACTBBioGRID30725116 details
IGFBP3KRT8BioGRID30725116 details
IGFBP3HNRNPA2B1BioGRID30725116 details
IGFBP3KRT7BioGRID30725116 details
IGFBP3H4C1BioGRID30725116 details
IGFBP3HMGN2BioGRID30725116 details
IGFBP3H2AC12BioGRID30725116 details
IGFBP3CUL4BIntAct23238014 details
IGFBP3EZH2IntAct23238014 details
IGFBP3NCOR1IntAct23518348 details
IGFBP3ARIntAct23518348 details