Entity Details

Primary name ITGAM
Entity type gene
Source Source Link

Details

PrimaryID3684
RefseqGeneNG_011719
SymbolITGAM
Nameintegrin subunit alpha M
Chromosome16
Location16p11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsITAM_HUMAN

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001774 microglial cell activation
GO:0001851 complement component C3b binding
GO:0005178 integrin binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0006898 receptor-mediated endocytosis
GO:0006911 phagocytosis, engulfment
GO:0007155 cell adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0008305 integrin complex
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010668 ectodermal cell differentiation
GO:0019221 cytokine-mediated signaling pathway
GO:0030198 extracellular matrix organization
GO:0030900 forebrain development
GO:0031072 heat shock protein binding
GO:0032930 positive regulation of superoxide anion generation
GO:0034142 toll-like receptor 4 signaling pathway
GO:0034688 integrin alphaM-beta2 complex
GO:0035579 specific granule membrane
GO:0038024 cargo receptor activity
GO:0043312 neutrophil degranulation
GO:0043315 positive regulation of neutrophil degranulation
GO:0044853 plasma membrane raft
GO:0045087 innate immune response
GO:0045963 negative regulation of dopamine metabolic process
GO:0046872 metal ion binding
GO:0050900 leukocyte migration
GO:0070062 extracellular exosome
GO:0070821 tertiary granule membrane
GO:0090314 positive regulation of protein targeting to membrane
GO:0097190 apoptotic signaling pathway
GO:0097242 amyloid-beta clearance
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules
GO:0110090 positive regulation of hippocampal neuron apoptotic process
GO:0150062 complement-mediated synapse pruning
GO:0150064 vertebrate eye-specific patterning
GO:1901216 positive regulation of neuron death
GO:1904151 positive regulation of microglial cell mediated cytotoxicity
GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling
GO:2000363 positive regulation of prostaglandin-E synthase activity

Diseases

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Interactions

65 interactions

InteractorPartnerSourcesPublicationsLink
ITGAMSLC10A6BioGRID, IntAct32296183 details
ITGAMCD79ABioGRID, IntAct32296183 details
ITGAMKCNJ6BioGRID, IntAct32296183 details
ITGAMKIR2DL3BioGRID, IntAct32296183 details
ITGAMTMX2BioGRID, IntAct32296183 details
ITGAMGJA8BioGRID, IntAct32296183 details
ITGAMTMEM52BBioGRID, IntAct32296183 details
ITGAMELOVL4BioGRID, IntAct32296183 details
ITGAMCERS4BioGRID, IntAct32296183 details
ITGAMSYT2BioGRID, IntAct32296183 details
ITGAMGJB1BioGRID, IntAct32296183 details
ITGAMRUSF1BioGRID, IntAct32296183 details
ITGAMGORABBioGRID, IntAct32296183 details
ITGAMAQP6BioGRID, IntAct32296183 details
ITGAMMGST3BioGRID, IntAct32296183 details
ITGAMERGIC3BioGRID, IntAct32296183 details
ITGAMHSD17B13BioGRID, IntAct32296183 details
ITGAMPIGPBioGRID, IntAct32296183 details
ITGAMDKK4BioGRID, IntAct32296183 details
ITGAMPGRMC2BioGRID, IntAct32296183 details
ITGAMSCN3BBioGRID, IntAct32296183 details
ITGAMMUC1BioGRID, IntAct32296183 details
ITGAMCLRN1BioGRID, IntAct32296183 details
ITGAMREEP4BioGRID, IntAct32296183 details
ITGAMTMEM229BBioGRID, IntAct32296183 details
ITGAMKASH5BioGRID, IntAct32296183 details
ITGAMCREB3L1BioGRID, IntAct32296183 details
ITGAMGPR42BioGRID, IntAct32296183 details
ITGAMMRM1BioGRID, IntAct32296183 details
ITGAMREEP2BioGRID, IntAct32296183 details
ITGAMTMEM14BBioGRID, IntAct32296183 details
ITGAMMMGT1BioGRID, IntAct32296183 details
ITGAMARL13BBioGRID, IntAct32296183 details
ITGAMABHD16ABioGRID, IntAct32296183 details
ITGAMSLC35C2BioGRID, IntAct32296183 details
ITGAMPTNUniProt28939773 details
ITGAMAUP1BioGRID12042322 details
ITGAMPLAURBioGRID, HPRD10744708 details
ITGAMICAM1BioGRID, HPRD11073102 12208882 9488691 details
ITGAMJAM3BioGRID, HPRD12208882 details
ITGAMBCAP31BioGRID15294914 details
ITGAMSHARPINBioGRID24210817 details
ITGAMLMNABioGRID24623722 details
ITGAMTMEM31BioGRID32296183 details
ITGAMCLEC4MMINT16246332 details
ITGAMCD177UniProt21193407 details
ITGAMITGB2HPRD, IntAct18083624 2454931 details
ITGAMPRTN3BioGRID12960243 details
ITGAMIRAK1BioGRID, HPRD11701612 details
ITGAMC3BioGRID, HPRD11073102 23134465 4062888 details
ITGAMAPOEBioGRID23134465 details
ITGAMAPPBioGRID23134465 details
ITGAMICAM4HPRD10846180 details
ITGAMELANEHPRD15718918 details
ITGAMTHY1HPRD15004192 details
ITGAMCFHHPRD9558116 details
ITGAMFGGHPRD11073102 9712878 details
ITGAMHPHPRD11967116 details
ITGAMICAM2HPRD10352278 details
ITGAMGP1BAHPRD10899906 details
ITGAMCD209HPRD16246332 details
ITGAMTEX101BioGRID, UniProt30097533 details
ITGAMRAD21BioGRID22145905 details
ITGAMNHLRC2BioGRID30397336 details
ITGAMDDX58BioGRID32513696 details