Entity Details

Primary name MMP2
Entity type gene
Source Source Link

Details

PrimaryID4313
RefseqGeneNG_008989
SymbolMMP2
Namematrix metallopeptidase 2
Chromosome16
Location16q12.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-03-18
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsMMP2_HUMAN

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001666 response to hypoxia
GO:0001955 blood vessel maturation
GO:0001957 intramembranous ossification
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0007566 embryo implantation
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0019221 cytokine-mediated signaling pathway
GO:0022617 extracellular matrix disassembly
GO:0030017 sarcomere
GO:0030198 extracellular matrix organization
GO:0030574 collagen catabolic process
GO:0034614 cellular response to reactive oxygen species
GO:0035987 endodermal cell differentiation
GO:0044267 cellular protein metabolic process
GO:0048013 ephrin receptor signaling pathway
GO:0048771 tissue remodeling
GO:0060325 face morphogenesis
GO:0060346 bone trabecula formation
GO:0062023 collagen-containing extracellular matrix
GO:0071230 cellular response to amino acid stimulus
GO:0071492 cellular response to UV-A
GO:1904645 response to amyloid-beta
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation

Diseases

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Interactions

73 interactions

InteractorPartnerSourcesPublicationsLink
MMP2TIMP2BioGRID, HPRD, IntAct10991943 12032297 12374789 28514442 9182583 9410885 9933646 details
MMP2SCUBE3I2D21441952 details
MMP2CAPN3BioGRID, IntAct23414517 details
MMP2TGFB1BioGRID, HPRD, IntAct10652271 25241761 details
MMP2A2MBioGRID, HPRD, IntAct25241761 9344465 details
MMP2COL5A1BioGRID, IntAct, matrixdb20979576 28514442 details
MMP2PCSK9MINT25613181 details
MMP2MTNR1ABioGRID, IntAct26514267 details
MMP2MTNR1BBioGRID, IntAct26514267 details
MMP2RELBioGRID, IntAct32296183 details
MMP2TIMP3BioGRID, HPRD, IntAct10196161 28514442 7782289 details
MMP2PCOLCEIntAct20207734 details
MMP2APPIntAct32814053 details
MMP2CCL7BioGRID, HPRD10947989 12149192 details
MMP2BCANBioGRID, HPRD10986281 details
MMP2COL1A1BioGRID, HPRD11368514 details
MMP2TIMP4BioGRID, HPRD12374789 9182583 details
MMP2THBS1BioGRID, HPRD10900205 details
MMP2THBS2BioGRID, HPRD10900205 details
MMP2PAK4BioGRID23254288 details
MMP2HSP90AA1BioGRID, HPRD, IntAct15146192 details
MMP2BACE1BioGRID, HPRD, IntAct12586836 25241761 details
MMP2COL18A1BioGRID, HPRD, IntAct12023034 28514442 details
MMP2DISC1IntAct31413325 details
MMP2ANXA2UniProt31210752 details
MMP2LCN2BioGRID, HPRD7683678 details
MMP2ITGAVBioGRID, HPRD11134507 22349830 23254288 details
MMP2ITGB1BioGRID22349830 details
MMP2ITGB3BioGRID23254288 details
MMP2STAT3BioGRID25219839 details
MMP2HAPLN1HPRD7694569 details
MMP2TIMP1HPRD12475252 details
MMP2COL7A1HPRD10652000 details
MMP2COL6A3HPRD8862926 details
MMP2FGFR1HPRD8692946 details
MMP2IGFBP3HPRD7523391 details
MMP2IL1BHPRD8663297 details
MMP2LGALS3HPRD7947821 details
MMP2MMP14HPRD14583471 8663332 details
MMP2CXCL12HPRD11571304 details
MMP2MMP17HPRD10551873 details
MMP2KISS1HPRD12879005 details
MMP2CLDN1HPRD11382769 details
MMP2MMP25HPRD14583471 8663332 details
MMP2SPOCK1HPRD12810672 details
MMP2DCNHPRD9148753 details
MMP2ACANHPRD7998967 details
MMP2EPHB2HPRD18713744 details
MMP2USP12BioGRID, IntAct19615732 details
MMP2OSBPL10BioGRID, IntAct19615732 details
MMP2MAP1LC3BIntAct20562859 details
MMP2CAND1BioGRID, IntAct21145461 details
MMP2LDLRMINT25613181 details
MMP2FN1BioGRID, IntAct28514442 details
MMP2COL12A1BioGRID, IntAct28514442 details
MMP2KLHL15BioGRID, IntAct28514442 details
MMP2EDABioGRID, IntAct28514442 details
MMP2COLEC12BioGRID, IntAct28514442 details
MMP2H2AC20BioGRID, IntAct28514442 details
MMP2COL4A6BioGRID, IntAct28514442 details
MMP2COL14A1BioGRID, IntAct28514442 details
MMP2COL6A2BioGRID, IntAct28514442 details
MMP2COL6A1BioGRID, IntAct28514442 details
MMP2COL4A2BioGRID, IntAct28514442 details
MMP2COL4A1BioGRID, IntAct28514442 details
MMP2COL2A1BioGRID, IntAct28514442 details
MMP2WFDC2UniProt31210752 details
MMP2RNF123BioGRID29676528 details
MMP2CUL4ABioGRID30945288 details
MMP2SMARCA4Molecular Connections20969766 details
MMP2SP1Molecular Connections20969766 details
MMP2MTDHBioGRID22199357 details
MMP2RC3H1BioGRID31451648 details