Entity Details

Primary name NR4A2
Entity type gene
Source Source Link

Details

PrimaryID4929
RefseqGeneNG_011821
SymbolNR4A2
Namenuclear receptor subfamily 4 group A member 2
Chromosome2
Location2q24.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-24
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsNR4A2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001666 response to hypoxia
GO:0001764 neuron migration
GO:0001975 response to amphetamine
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0007165 signal transduction
GO:0008013 beta-catenin binding
GO:0008270 zinc ion binding
GO:0008344 adult locomotory behavior
GO:0009791 post-embryonic development
GO:0016607 nuclear speck
GO:0021952 central nervous system projection neuron axonogenesis
GO:0021953 central nervous system neuron differentiation
GO:0021986 habenula development
GO:0031668 cellular response to extracellular stimulus
GO:0032991 protein-containing complex
GO:0034599 cellular response to oxidative stress
GO:0035259 glucocorticoid receptor binding
GO:0042053 regulation of dopamine metabolic process
GO:0042416 dopamine biosynthetic process
GO:0042551 neuron maturation
GO:0043085 positive regulation of catalytic activity
GO:0043524 negative regulation of neuron apoptotic process
GO:0043576 regulation of respiratory gaseous exchange
GO:0045444 fat cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046965 retinoid X receptor binding
GO:0046982 protein heterodimerization activity
GO:0051866 general adaptation syndrome
GO:0060070 canonical Wnt signaling pathway
GO:0071376 cellular response to corticotropin-releasing hormone stimulus
GO:0071542 dopaminergic neuron differentiation
GO:1904948 midbrain dopaminergic neuron differentiation
GO:1990837 sequence-specific double-stranded DNA binding
GO:2001234 negative regulation of apoptotic signaling pathway

Diseases

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Interactions

40 interactions

InteractorPartnerSourcesPublicationsLink
NR4A2TCEAL5BioGRID, IntAct20195357 details
NR4A2BAZ1BBioGRID, IntAct20195357 details
NR4A2CDKN2DBioGRID, IntAct25416956 31515488 32296183 details
NR4A2ODAD2BioGRID, IntAct32296183 details
NR4A2APPIntAct32814053 details
NR4A2RXRBBioGRID, HPRD, IntAct15604093 20211142 7705655 7758108 details
NR4A2SMARCA4BioGRID17043312 details
NR4A2SMARCA2BioGRID17043312 details
NR4A2RXRABioGRID, HPRD15604093 7705655 7758108 details
NR4A2COPS5BioGRID, HPRD15604093 details
NR4A2PPARGBioGRID11877444 details
NR4A2MAPK1BioGRID17681692 details
NR4A2PIAS4HPRD14559918 details
NR4A2GTF2IIntAct20195357 details
NR4A2CISD1IntAct20195357 details
NR4A2RANIntAct20195357 details
NR4A2ZCCHC17IntAct20195357 details
NR4A2ZNF41IntAct20195357 details
NR4A2OPA1IntAct20195357 details
NR4A2NDUFS5IntAct20195357 details
NR4A2ANP32EIntAct20195357 details
NR4A2NEFMIntAct20195357 details
NR4A2EIF3AIntAct20195357 details
NR4A2SUGP2IntAct20195357 details
NR4A2FDX1IntAct20195357 details
NR4A2SFPQBioGRID19144721 details
NR4A2NCOR2BioGRID19144721 details
NR4A2SIN3ABioGRID19144721 details
NR4A2RUNX1BioGRID21468021 details
NR4A2NCOA1BioGRID21757690 details
NR4A2PPARGC1ABioGRID21757690 details
NR4A2MAPK3BioGRID17681692 details
NR4A2CDKN1CHPRD14671317 details
NR4A2RPS6KA1HPRD16223362 details
NR4A2VHLHPRD18305400 details
NR4A2CCL15IntAct33179750 details
NR4A2CCL20IntAct33179750 details
NR4A2IFNA5IntAct33179750 details
NR4A2IL20IntAct33179750 details
NR4A2ELAVL1BioGRID19322201 details