| Disease ID | Source | Name | Description |
| 604928 | OMIM | Wolfram syndrome 2 (WFS2) | A rare disorder characterized by juvenile-onset insulin-dependent diabetes mellitus with optic atrophy. Other manifestations include diabetes insipidus, sensorineural deafness, dementia, psychiatric illnesses. WFS2 patients additionally show a strong bleeding tendency and gastrointestinal ulceration. Diabetes insipidus may be absent. The disease is caused by variants affecting the gene represented in this entry. |