Entity Details

Primary name PAX2
Entity type gene
Source Source Link

Details

PrimaryID5076
RefseqGeneNG_008680
SymbolPAX2
Namepaired box 2
Chromosome10
Location10q24.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-05-07
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsPAX2_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001655 urogenital system development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001709 cell fate determination
GO:0001823 mesonephros development
GO:0001843 neural tube closure
GO:0002072 optic cup morphogenesis involved in camera-type eye development
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003406 retinal pigment epithelium development
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005764 lysosome
GO:0005815 microtubule organizing center
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007409 axonogenesis
GO:0007501 mesodermal cell fate specification
GO:0007568 aging
GO:0007601 visual perception
GO:0008134 transcription factor binding
GO:0010001 glial cell differentiation
GO:0021554 optic nerve development
GO:0021631 optic nerve morphogenesis
GO:0021633 optic nerve structural organization
GO:0021650 vestibulocochlear nerve formation
GO:0031667 response to nutrient levels
GO:0032991 protein-containing complex
GO:0032993 protein-DNA complex
GO:0034451 centriolar satellite
GO:0035566 regulation of metanephros size
GO:0035799 ureter maturation
GO:0039003 pronephric field specification
GO:0042472 inner ear morphogenesis
GO:0043010 camera-type eye development
GO:0043066 negative regulation of apoptotic process
GO:0043069 negative regulation of programmed cell death
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043491 protein kinase B signaling
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048793 pronephros development
GO:0048854 brain morphogenesis
GO:0048856 anatomical structure development
GO:0048863 stem cell differentiation
GO:0050679 positive regulation of epithelial cell proliferation
GO:0060231 mesenchymal to epithelial transition
GO:0061360 optic chiasma development
GO:0070301 cellular response to hydrogen peroxide
GO:0071300 cellular response to retinoic acid
GO:0071333 cellular response to glucose stimulus
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0072075 metanephric mesenchyme development
GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0072162 metanephric mesenchymal cell differentiation
GO:0072179 nephric duct formation
GO:0072189 ureter development
GO:0072205 metanephric collecting duct development
GO:0072207 metanephric epithelium development
GO:0072221 metanephric distal convoluted tubule development
GO:0072289 metanephric nephron tubule formation
GO:0072300 positive regulation of metanephric glomerulus development
GO:0072305 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation
GO:0072593 reactive oxygen species metabolic process
GO:0090102 cochlea development
GO:0090103 cochlea morphogenesis
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis
GO:1900212 negative regulation of mesenchymal cell apoptotic process involved in metanephros development
GO:1900215 negative regulation of apoptotic process involved in metanephric collecting duct development
GO:1900218 negative regulation of apoptotic process involved in metanephric nephron tubule development
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000378 negative regulation of reactive oxygen species metabolic process
GO:2000594 positive regulation of metanephric DCT cell differentiation
GO:2000597 positive regulation of optic nerve formation

Diseases

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Interactions

27 interactions

InteractorPartnerSourcesPublicationsLink
PAX2BBS1BioGRID, IntAct18000879 details
PAX2BBS4BioGRID, IntAct18000879 details
PAX2BBS2BioGRID, IntAct18000879 details
PAX2BBS7BioGRID, IntAct18000879 details
PAX2BEX1BioGRID, MINT25640309 details
PAX2BLIDBioGRID, MINT25640309 details
PAX2GLCEBioGRID, MINT25640309 details
PAX2IL13RA2BioGRID, MINT25640309 details
PAX2KLK6BioGRID, MINT25640309 details
PAX2KLK9BioGRID, MINT25640309 details
PAX2MRC2BioGRID, MINT25640309 details
PAX2PRDM14BioGRID, MINT25640309 details
PAX2RASL10BBioGRID, MINT25640309 details
PAX2SNAI1BioGRID, MINT25640309 details
PAX2TRIM25BioGRID, MINT25640309 details
PAX2VPS45BioGRID, MINT25640309 details
PAX2NSD3BioGRID, MINT25640309 details
PAX2LMX1BUniProt15785774 details
PAX2MAPK8BioGRID, HPRD11700324 details
PAX2PAXIP1BioGRID, HPRD10908331 details
PAX2MAPK8IP1BioGRID, HPRD11700324 details
PAX2BRCA1BioGRID21880590 details
PAX2RB1BioGRID, HPRD12200151 details
PAX2WT1HPRD14603255 details
PAX2SFRP2HPRD14561758 details
PAX2ID2HPRD11134340 details
PAX2MKRN2BioGRID32460013 details