Entity Details

Primary name PDE8A
Entity type gene
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Details

PrimaryID5151
RefseqGeneNG_029630
SymbolPDE8A
Namephosphodiesterase 8A
Chromosome15
Location15q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-11-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPDE8A_HUMAN

GO terms

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GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005829 cytosol
GO:0006198 cAMP catabolic process
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0019900 kinase binding
GO:0046872 metal ion binding
GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity
GO:0060548 negative regulation of cell death
GO:0070062 extracellular exosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071364 cellular response to epidermal growth factor stimulus
GO:1903206 negative regulation of hydrogen peroxide-induced cell death

Diseases

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Interactions

10 interactions