Entity Details

Primary name ATP7A
Entity type gene
Source Source Link

Details

PrimaryID538
RefseqGeneNG_013224
SymbolATP7A
NameATPase copper transporting alpha
ChromosomeX
LocationXq21.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-11-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsATP7A_HUMAN

GO terms

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GOName
GO:0001568 blood vessel development
GO:0001701 in utero embryonic development
GO:0001889 liver development
GO:0001974 blood vessel remodeling
GO:0002082 regulation of oxidative phosphorylation
GO:0005375 copper ion transmembrane transporter activity
GO:0005507 copper ion binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005770 late endosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0006568 tryptophan metabolic process
GO:0006584 catecholamine metabolic process
GO:0006825 copper ion transport
GO:0006878 cellular copper ion homeostasis
GO:0007005 mitochondrion organization
GO:0007565 female pregnancy
GO:0007595 lactation
GO:0007626 locomotory behavior
GO:0010041 response to iron(III) ion
GO:0010042 response to manganese ion
GO:0010043 response to zinc ion
GO:0010273 detoxification of copper ion
GO:0010468 regulation of gene expression
GO:0010592 positive regulation of lamellipodium assembly
GO:0014069 postsynaptic density
GO:0015677 copper ion import
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016532 superoxide dismutase copper chaperone activity
GO:0018205 peptidyl-lysine modification
GO:0019430 removal of superoxide radicals
GO:0019730 antimicrobial humoral response
GO:0021702 cerebellar Purkinje cell differentiation
GO:0021860 pyramidal neuron development
GO:0021954 central nervous system neuron development
GO:0030140 trans-Golgi network transport vesicle
GO:0030141 secretory granule
GO:0030198 extracellular matrix organization
GO:0030199 collagen fibril organization
GO:0030424 axon
GO:0030425 dendrite
GO:0030670 phagocytic vesicle membrane
GO:0031069 hair follicle morphogenesis
GO:0031252 cell leading edge
GO:0031267 small GTPase binding
GO:0031526 brush border membrane
GO:0031901 early endosome membrane
GO:0032588 trans-Golgi network membrane
GO:0032767 copper-dependent protein binding
GO:0032773 positive regulation of monophenol monooxygenase activity
GO:0033162 melanosome membrane
GO:0034220 ion transmembrane transport
GO:0034760 negative regulation of iron ion transmembrane transport
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0042093 T-helper cell differentiation
GO:0042414 epinephrine metabolic process
GO:0042415 norepinephrine metabolic process
GO:0042417 dopamine metabolic process
GO:0042428 serotonin metabolic process
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043085 positive regulation of catalytic activity
GO:0043204 perikaryon
GO:0043473 pigmentation
GO:0043588 skin development
GO:0043682 P-type divalent copper transporter activity
GO:0045121 membrane raft
GO:0045793 positive regulation of cell size
GO:0048023 positive regulation of melanin biosynthetic process
GO:0048251 elastic fiber assembly
GO:0048286 lung alveolus development
GO:0048471 perinuclear region of cytoplasm
GO:0048812 neuron projection morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051087 chaperone binding
GO:0051216 cartilage development
GO:0051353 positive regulation of oxidoreductase activity
GO:0051542 elastin biosynthetic process
GO:0060003 copper ion export
GO:0071230 cellular response to amino acid stimulus
GO:0071236 cellular response to antibiotic
GO:0071276 cellular response to cadmium ion
GO:0071279 cellular response to cobalt ion
GO:0071280 cellular response to copper ion
GO:0071281 cellular response to iron ion
GO:0071284 cellular response to lead ion
GO:0071456 cellular response to hypoxia
GO:0140581 P-type monovalent copper transporter activity
GO:1903036 positive regulation of response to wounding
GO:1903136 cuprous ion binding
GO:1904754 positive regulation of vascular associated smooth muscle cell migration
GO:1904959 regulation of cytochrome-c oxidase activity

Diseases

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Interactions

48 interactions

InteractorPartnerSourcesPublicationsLink
ATP7APDZD11HPRD, MINT16051599 details
ATP7AATOX1BioGRID, HPRD, matrixdb10497213 10557326 12679332 31932435 details
ATP7AGLRXBioGRID16884690 details
ATP7ALOXmatrixdb31932435 details
ATP7ACLUBioGRID21242307 details
ATP7ACOMMD1BioGRID22130675 details
ATP7ASNX27BioGRID31541095 details
ATP7ACPHPRD11040994 details
ATP7APLK1BioGRID, IntAct26496610 details
ATP7ATMEM17BioGRID, IntAct26638075 details
ATP7AC3AR1BioGRID, IntAct28514442 details
ATP7ACLEC2DBioGRID, IntAct28514442 details
ATP7ARPS27BioGRID, IntAct28514442 details
ATP7ALAMP3BioGRID, IntAct28514442 34079125 details
ATP7ANCR3LG1BioGRID, IntAct28514442 details
ATP7AAPBB2BioGRID, IntAct26186194 28514442 details
ATP7ACOG6BioGRID, IntAct28514442 details
ATP7ACD83BioGRID, IntAct28514442 details
ATP7AITM2ABioGRID, IntAct28514442 details
ATP7ARAB29BioGRID, IntAct28514442 details
ATP7ACOG5BioGRID, IntAct28514442 details
ATP7ATGOLN2BioGRID, IntAct29568061 details
ATP7AHNRNPDBioGRID, IntAct30021884 details
ATP7ACD9UniProt26686862 details
ATP7AACIN1BioGRID22939629 details
ATP7ADNAJB2BioGRID26186194 details
ATP7ALGALS9BioGRID26186194 details
ATP7ANTRK1BioGRID25921289 details
ATP7AHRASBioGRID30442766 details
ATP7AKRASBioGRID30442766 34079125 details
ATP7ANRASBioGRID30442766 details
ATP7ADNAJC5BioGRID33957083 details
ATP7AC11orf52BioGRID34079125 details
ATP7ADIRAS3BioGRID34079125 details
ATP7AGJA1BioGRID34079125 details
ATP7AGJD3BioGRID34079125 details
ATP7ALAMP1BioGRID34079125 details
ATP7ALAMP2BioGRID34079125 details
ATP7ALAMTOR1BioGRID34079125 details
ATP7ALYNBioGRID34079125 details
ATP7AOCLNBioGRID34079125 details
ATP7ARAB2ABioGRID34079125 details
ATP7ARAB35BioGRID34079125 details
ATP7ARAB4ABioGRID34079125 details
ATP7ARAB5CBioGRID34079125 details
ATP7ARHOBBioGRID34079125 details
ATP7ASTX7BioGRID34079125 details
ATP7AVIRMABioGRID29507755 details