Entity Details

Primary name PARP16
Entity type gene
Source Source Link

Details

PrimaryID54956
RefseqGene
SymbolPARP16
Namepoly(ADP-ribose) polymerase family member 16
Chromosome15
Location15q22.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPAR16_HUMAN

GO terms

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GOName
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005635 nuclear envelope
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006471 protein ADP-ribosylation
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0019082 viral protein processing
GO:0019900 kinase binding
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway
GO:0036498 IRE1-mediated unfolded protein response
GO:0043539 protein serine/threonine kinase activator activity
GO:0060548 negative regulation of cell death
GO:0070213 protein auto-ADP-ribosylation
GO:0071782 endoplasmic reticulum tubular network
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:0140289 protein mono-ADP-ribosylation
GO:1990404 protein ADP-ribosylase activity
GO:1990830 cellular response to leukemia inhibitory factor

Diseases

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Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
PARP16NEDD4BioGRID19953087 details
PARP16GMCL1BioGRID25416956 details
PARP16ST7BioGRID29395067 details
PARP16KLC4BioGRID, IntAct26496610 details
PARP16DOT1LBioGRID, IntAct26496610 details
PARP16PCIF1BioGRID, IntAct26496610 details
PARP16MLKLBioGRID, IntAct26496610 details
PARP16ZNF644BioGRID, IntAct26496610 details
PARP16MRPL1BioGRID, IntAct26496610 details
PARP16COG6BioGRID, IntAct26186194 28514442 details
PARP16COG5BioGRID, IntAct26186194 28514442 details
PARP16RAI14BioGRID, IntAct26186194 28514442 details
PARP16MDN1BioGRID, IntAct26186194 28514442 details
PARP16COG1BioGRID, IntAct26186194 28514442 details
PARP16NEDD1BioGRID, IntAct26186194 28514442 details
PARP16B3GALNT2BioGRID, IntAct26186194 28514442 details
PARP16UBE4ABioGRID, IntAct26186194 28514442 details
PARP16LRP6BioGRID, IntAct26186194 28514442 details
PARP16LRP5BioGRID, IntAct26186194 28514442 details
PARP16VWA8BioGRID, IntAct26186194 28514442 details
PARP16HACD3BioGRID, MINT24981860 details
PARP16NDUFA4BioGRID, MINT24981860 details
PARP16EMDBioGRID, MINT24981860 34079125 details
PARP16SLC7A5BioGRID, MINT24981860 details
PARP16PGRMC1BioGRID, MINT24981860 details
PARP16DDX20BioGRID26186194 details
PARP16ECSITBioGRID26186194 details
PARP16VAC14BioGRID26186194 details
PARP16LRBABioGRID26186194 details
PARP16CRELD1BioGRID26186194 details
PARP16RECQL4BioGRID29229926 details
PARP16OTULINLBioGRID31056421 details
PARP16NPC1BioGRID33144569 details
PARP16RPN2BioGRID34079125 details
PARP16SEC61BBioGRID34079125 details
PARP16SEC62BioGRID34079125 details
PARP16TRIM25BioGRID29117863 details