Entity Details

Primary name AURKC
Entity type gene
Source Source Link

Details

PrimaryID6795
RefseqGeneNG_012134
SymbolAURKC
Nameaurora kinase C
Chromosome19
Location19q13.43
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAURKC_HUMAN

GO terms

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GOName
GO:0000775 chromosome, centromeric region
GO:0000793 condensed chromosome
GO:0004672 protein kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005876 spindle microtubule
GO:0006468 protein phosphorylation
GO:0007052 mitotic spindle organization
GO:0007283 spermatogenesis
GO:0008608 attachment of spindle microtubules to kinetochore
GO:0016570 histone modification
GO:0030496 midbody
GO:0031616 spindle pole centrosome
GO:0032133 chromosome passenger complex
GO:0032465 regulation of cytokinesis
GO:0032467 positive regulation of cytokinesis
GO:0035174 histone serine kinase activity
GO:0048599 oocyte development
GO:0051233 spindle midzone
GO:0051256 mitotic spindle midzone assembly
GO:0051301 cell division
GO:0051321 meiotic cell cycle
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Diseases

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Disease IDSourceNameDescription
243060 OMIMSpermatogenic failure 5 (SPGF5)An infertility disorder caused by spermatogenesis defects. Semen from affected men show close to 100% morphologically abnormal multiflagellar spermatozoa with low motility, oversized irregular heads, and abnormal midpiece and acrosome. The disease is caused by variants affecting the gene represented in this entry.