Entity Details

Primary name PAR15_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ460N3
EntryNamePAR15_HUMAN
FullNameProtein mono-ADP-ribosyltransferase PARP15
TaxID9606
Evidenceevidence at protein level
Length678
SequenceStatuscomplete
DateCreated2006-10-17
DateModified2021-06-02

Ontological Relatives

GenesPARP15

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003714 transcription corepressor activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0010629 negative regulation of gene expression
GO:0070212 protein poly-ADP-ribosylation
GO:0070403 NAD+ binding
GO:0140289 protein mono-ADP-ribosylation
GO:1990404 protein ADP-ribosylase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002589 Macro domainDomainDomain
IPR012317 Poly(ADP-ribose) polymerase, catalytic domainDomainDomain
IPR034401 Protein mono-ADP-ribosyltransferase PARP15FamilyFamily
IPR043472 Macro domain-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB08348 N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDEDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
PAR15_HUMANNRM_HUMANBioGRID, IntAct32296183 details
PAR15_HUMANA4_HUMANBioGRID21832049 details
PAR15_HUMANPAR15_HUMANHPRD16061477 details