Entity Details

Primary name TIMP2
Entity type gene
Source Source Link

Details

PrimaryID7077
RefseqGene
SymbolTIMP2
NameTIMP metallopeptidase inhibitor 2
Chromosome17
Location17q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-11-27
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsTIMP2_HUMAN

GO terms

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GOName
GO:0002020 protease binding
GO:0004857 enzyme inhibitor activity
GO:0005178 integrin binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007417 central nervous system development
GO:0007568 aging
GO:0008191 metalloendopeptidase inhibitor activity
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell population proliferation
GO:0009725 response to hormone
GO:0009986 cell surface
GO:0010033 response to organic substance
GO:0010951 negative regulation of endopeptidase activity
GO:0022617 extracellular matrix disassembly
GO:0030414 peptidase inhibitor activity
GO:0030426 growth cone
GO:0031012 extracellular matrix
GO:0032487 regulation of Rap protein signal transduction
GO:0034097 response to cytokine
GO:0035580 specific granule lumen
GO:0042493 response to drug
GO:0043025 neuronal cell body
GO:0043312 neutrophil degranulation
GO:0043410 positive regulation of MAPK cascade
GO:0045666 positive regulation of neuron differentiation
GO:0045762 positive regulation of adenylate cyclase activity
GO:0045930 negative regulation of mitotic cell cycle
GO:0046580 negative regulation of Ras protein signal transduction
GO:0051045 negative regulation of membrane protein ectodomain proteolysis
GO:0062023 collagen-containing extracellular matrix
GO:1904724 tertiary granule lumen
GO:1904813 ficolin-1-rich granule lumen
GO:1905049 negative regulation of metallopeptidase activity

Diseases

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