Entity Details

Primary name SETDB2
Entity type gene
Source Source Link

Details

PrimaryID83852
RefseqGene
SymbolSETDB2
NameSET domain bifurcated histone lysine methyltransferase 2
Chromosome13
Location13q14.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-06
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSETB2_HUMAN

GO terms

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GOName
GO:0000278 mitotic cell cycle
GO:0001947 heart looping
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol
GO:0007059 chromosome segregation
GO:0008270 zinc ion binding
GO:0010629 negative regulation of gene expression
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046974 histone methyltransferase activity (H3-K9 specific)
GO:0051301 cell division
GO:0051567 histone H3-K9 methylation
GO:0070828 heterochromatin organization
GO:0070986 left/right axis specification
GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly

Diseases

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Interactions

12 interactions

InteractorPartnerSourcesPublicationsLink
SETDB2ARL14EPBioGRID, IntAct25416956 28514442 31515488 32296183 details
SETDB2SENP7BioGRID, IntAct28514442 details
SETDB2LRRC15BioGRID, IntAct28514442 details
SETDB2DSG4BioGRID, IntAct28514442 details
SETDB2LYG2BioGRID, IntAct28514442 details
SETDB2HEPHL1BioGRID, IntAct28514442 details
SETDB2SELENBP1BioGRID, IntAct28514442 details
SETDB2ZNF445BioGRID, IntAct28514442 details
SETDB2DUSP14BioGRID, IntAct28514442 details
SETDB2DHX16BioGRID, IntAct28514442 details
SETDB2NDUFV3BioGRID, IntAct30021884 details
SETDB2SP110BioGRID31753913 details