Entity Details

Primary name MCM8
Entity type gene
Source Source Link

Details

PrimaryID84515
RefseqGeneNG_042869
SymbolMCM8
Nameminichromosome maintenance 8 homologous recombination repair factor
Chromosome20
Location20p12.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-27
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsMCM8_HUMAN

GO terms

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GOName
GO:0000724 double-strand break repair via homologous recombination
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0003688 DNA replication origin binding
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0006974 cellular response to DNA damage stimulus
GO:0007049 cell cycle
GO:0007292 female gamete generation
GO:0016787 hydrolase activity
GO:0019899 enzyme binding
GO:0032406 MutLbeta complex binding
GO:0032407 MutSalpha complex binding
GO:0032408 MutSbeta complex binding
GO:0036298 recombinational interstrand cross-link repair
GO:0036388 pre-replicative complex assembly
GO:0042555 MCM complex
GO:0048232 male gamete generation
GO:0050821 protein stabilization
GO:0071168 protein localization to chromatin
GO:0097362 MCM8-MCM9 complex

Diseases

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Interactions

39 interactions

InteractorPartnerSourcesPublicationsLink
MCM8FEM1CBioGRID, IntAct32296183 details
MCM8MCM9BioGRID, IntAct23401855 26186194 26215093 26300262 26870752 28514442 details
MCM8MCMBPBioGRID, IntAct, MINT22540012 24299456 25036637 details
MCM8MCM4BioGRID, HPRD12771218 details
MCM8MCM6BioGRID, HPRD12771218 details
MCM8MCM7BioGRID, HPRD12771218 details
MCM8CDC6BioGRID15684404 details
MCM8ORC2BioGRID15684404 details
MCM8MCM8BioGRID22771115 details
MCM8RAD50BioGRID26215093 details
MCM8MSH2BioGRID26300262 details
MCM8MLH1BioGRID26300262 details
MCM8RAD51BioGRID23401855 details
MCM8FAM167ABioGRID, IntAct28514442 details
MCM8VWA5ABioGRID, IntAct28514442 details
MCM8BPNT1BioGRID, IntAct28514442 details
MCM8KLK5BioGRID, IntAct26186194 28514442 details
MCM8P4HA2BioGRID, IntAct28514442 details
MCM8AVILBioGRID, IntAct28514442 details
MCM8F9BioGRID, IntAct28514442 details
MCM8IL17RABioGRID, IntAct28514442 details
MCM8PSG8BioGRID, IntAct28514442 details
MCM8SNX21BioGRID, IntAct28514442 details
MCM8KLHL40BioGRID, IntAct28514442 details
MCM8TSPYL6BioGRID, IntAct28514442 details
MCM8DEF8BioGRID, IntAct28514442 details
MCM8SKP2BioGRID, IntAct28514442 details
MCM8TUBBBioGRID, IntAct28514442 details
MCM8IQCF1BioGRID, IntAct28514442 details
MCM8LRRC27BioGRID, IntAct28514442 details
MCM8HSPA5BioGRID, IntAct30021884 details
MCM8MRPS25BioGRID, MINT24981860 details
MCM8SKAP1BioGRID26186194 details
MCM8XPO1BioGRID26673895 details
MCM8MYCNBioGRID19997598 details
MCM8SMARCA2BioGRID31753913 details
MCM8CUL4BIntAct23238014 details
MCM8EZH2IntAct23238014 details
MCM8HNRNPLBioGRID28611215 details