Entity Details

Primary name LGI1
Entity type gene
Source Source Link

Details

PrimaryID9211
RefseqGeneNG_011832
SymbolLGI1
Nameleucine rich glioma inactivated 1
Chromosome10
Location10q23.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-02-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsLGI1_HUMAN

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0030307 positive regulation of cell growth
GO:0031175 neuron projection development
GO:0043083 synaptic cleft
GO:0050806 positive regulation of synaptic transmission
GO:0098978 glutamatergic synapse
GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane

Diseases

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Disease IDSourceNameDescription
600512 OMIMEpilepsy, familial temporal lobe, 1 (ETL1)A focal form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe. Seizures are usually accompanied by sensory symptoms, most often auditory in nature. The disease is caused by variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
LGI1DLG4BioGRID16990550 details
LGI1ADAM22BioGRID, HPRD16990550 details